Sartorius Biostat B Dual Control Bioreactor with 2-Liter Jacketed Autoclavable Vessels for Microbial Cultures

The Sartorius Biostat B Dual Control Bioreactor is a rigorously tested bench-top bioreactor system designed for microbial fermentation and bioprocess development with two 2-liter jacketed, autoclavable glass vessels. Engineered for precise control and reproducibility in laboratory-scale bioprocessing, it supports critical biotechnology workflows including molecular diagnostics, synthetic biology, and biopharmaceutical production.

Key technical features include:

• Dual 2 L jacketed glass vessels supporting working volumes from 0.6 to 2 L with robust temperature regulation via a 600 W heating module and double-wall jacketing ensuring uniform temperature control up to 80 °C.
• Advanced agitation system with two direct-drive 200 W motors allowing a wide stirring speed range of 20–2000 RPM, optimized for microbial culture homogenization and shear-sensitive bioprocesses.
• Integrated gas flow control equipped with two thermal mass flow controllers (TMFCs) for Air and O₂, enabling precision aeration via spargers with ±1% full scale accuracy, essential for oxygen transfer rate (OTR) optimization in aerobic fermentations.
• Built-in Watson Marlow 114 peristaltic pumps provide fixed-speed dosing for acid/base adjustments and substrate feeding, facilitating pH control and fed-batch processes with programmable flow rates.
• Comprehensive sensor integration includes high-accuracy pH and dissolved oxygen (DO) probes, Pt100 temperature sensors, with multiple digital I/O ports supporting process monitoring, gravimetric feeding control, and biomass sensing via optional BioPAT ViaMass inline technology.
• Compact footprint (35×82.2×43 cm) and 55 kg weight for efficient laboratory space utilization, powered by standard 120 V, 60 Hz electrical supply.

The Biostat B system is widely adopted in biotechnology research fields such as live-cell imaging adjuncts, bioprocess optimization, and clinical diagnostics. The system’s dual-vessel configuration enables parallel batch or fed-batch microbial culture runs, ideal for process development, scale-up studies, and gene editing strain cultivation.

Additional options include external Watson Marlow pump upgrades, alternative impeller configurations, and integration with chillers for advanced temperature modulation.

This bioreactor controller is fully serviced, calibrated using NIST-traceable standards, and shipped with a warranty and post-sale technical support, ensuring reliable operation in demanding biomanufacturing and synthetic biology environments.

Ideal applications:

• Microbial fermentation and culture growth experiments
• Controlled batch and fed-batch cultivation in biotechnology labs
• Process development for biopharmaceutical and industrial microbiology pipelines
• Laboratory-scale bioprocess monitoring with scalable parameter control

The Sartorius Biostat B represents a robust, precision-engineered solution essential for high-fidelity microbial bioprocessing and is a critical instrument for researchers focused on bioprocess control and biomanufacturing optimization.