Sartorius Biostat B-DCU 4-Fold Single-Use Cell Culture Bioreactor System with Univessel SU Vessels

The Sartorius Biostat B-DCU 4-Fold Cell Culture Univessel SU Bioreactor System is a modular and compact bioprocess control platform designed for parallel small-scale upstream development in biotechnology and molecular diagnostics. This system supports *four independent single-use bioreactor vessels* simultaneously, each with individual control over critical parameters including temperature, pH, and dissolved oxygen (DO), essential for stable and reproducible mammalian and microbial cell cultures.

Key technical features include:

• Bioreactor stations (4x): Each equipped with agitator motors delivering agitation speeds from *20 to 2000 RPM* (20–400 RPM for 2L Univessel SU), direct coupling to stirrer shafts, and dual 3-blade segment impellers angled at 30° for efficient mixing.
• Univessel SU single-use vessels: Working volume ranging from *0.6 to 2 L*, ideal for batch and fed-batch cultivation; vessels incorporate L-sparger aeration technology for controlled gas dispersion.
• Integrated gas flow supply: Includes 5 thermal mass flow controllers (TMFC) with ±0.3% full-scale precision managing Air, O2, N2, and CO2 flows up to 1.5 barg, supporting precise process gas composition adjustments critical in cell line development and biomanufacturing.
• Temperature control: External heating blankets provide up to 50°C control range with 185W power, ensuring stable culture environment and temperature homogeneity.
• Peristaltic pump system: Equipped with 3 Watson Marlow 114 Easy Load pumps for substrate delivery and medium exchange, supporting rpm ranges tailored to flexible feeding strategies.
• Advanced digital connectivity: Multiple M12 ports and RS-232/485 interfaces allow integration with auxiliary sensors, balances, BioPAT® Viamass biomass sensors, and communication protocols such as Modbus and OPC, enabling enhanced process monitoring and automation.
• Compact dimensions: Footprint of approximately 360×768×432 mm with a net weight of 45 kg makes the system suitable for laboratory benchtops and pilot-scale bioprocessing.
• Operational versatility: Widely used in biotechnology research domains including synthetic biology, gene editing workflows, and biopharmaceutical production pipelines, the system supports parallel cell line development, process optimization, scale-down validation, and small-scale upstream bioprocess development.

This bioreactor system is critical for biotechnology and pharmaceutical labs seeking to optimize cell culture conditions with precise control over bioprocess parameters in a reliable, single-use format that minimizes contamination risks and cleaning procedures. Its modular and flexible design allows adaptation for specialized research areas such as molecular diagnostics and bioprocess engineering.

Applications include:

• Parallel cell line and clone development
• Process development and optimization for upstream bioprocesses
• Batch and fed-batch mammalian and microbial cultivation
• Scale-down model validation for biopharmaceutical manufacturing
• Synthetic biology and gene editing culture workflows

Additional notes: Consumables such as the Univessel SU single-use vessels are not included but essential for operation. The system is sold fully tested, serviced, and functional with a 120-day U.S. warranty and 60-day international warranty, including remote setup consultation and training. Robust service and technical support are provided to ensure high uptime and reproducible experiment outcomes.

This system aligns with industry standards for single-use bioreactors integral to modern bioprocessing laboratories focused on biotechnology innovation, cell imaging applications requiring controlled environments, and scalable biomanufacturing workflows.