Eppendorf DASbox Mini Bioreactor System Unit 1 for Parallel Small-Scale Cell Culture

The Eppendorf DASbox Mini Bioreactor System Unit 1 is a compact and versatile laboratory bioprocessing platform designed for parallel small-scale cell culture applications, supporting up to 4 bioreactors operating in parallel. This system is engineered for precise control and monitoring of key process parameters crucial in biotechnology workflows such as molecular diagnostics, gene editing, and synthetic biology research.

Key technical specifications include:

• Parallel operation of 4 bioreactors with working volumes ranging from 60–250 mL for glass vessels and 100–250 mL for single-use vessels (consumables not included).
• Agitation speeds adaptable between 20–2,500 rpm (glass vessels) and 20–500 rpm or 20–200 rpm for single-use vessels with pitched blade or 8-blade impellers, respectively.
• Liquid-free Peltier-based temperature control, allowing temperature settings from 10°C to 60°C (glass vessels) and 10°C to 45°C (single-use vessels), suitable for sensitive mammalian and insect cell lines.
• Gas flow control via thermal mass flow controllers (TMFC) enabling mixed gas feeds of Air, N2, O2, CO2, with flow rates up to 5 sL/h (CO2 up to 3.5 sL/h), essential for optimized aerobic and anaerobic culture conditions.
• Integrated pH and dissolved oxygen (DO) sensors with cascade control mechanisms that support automated modulation of gas concentrations and feed base for process stability.
• Modular configuration facilitates scale-down process development and bioprocess optimization experiments widely adopted in biopharmaceutical production pipelines and cell-based biomanufacturing workflows.

This system is critical for early-stage cell cultivation, media and feeding strategy optimization, and scale-down modeling of large-scale bioreactors in biotechnology and clinical diagnostics laboratories. Its capability to run multiple bioreactors simultaneously makes it an essential tool for parallel bioprocess development and high-throughput screening in synthetic biology and cell line development.

Note: The unit is supplied without consumables, reaction vessels, or software. It is sold as-is, without warranty or returns due to the lack of software and limited testing. Suitable for labs with existing consumables and software infrastructure or for parts and upgrading purposes.

The Eppendorf DASbox Mini Bioreactor system is widely recognized for its robust design and reliable parameter control, making it popular among molecular biology and bioprocess researchers focusing on live-cell culture, bioprocess monitoring, and advanced cell-based assays.