Cytiva Xuri W25 Cell Expansion System with Tray 20 for Controlled Cell Expansion

The Cytiva Xuri W25 Cell Expansion System w/ Tray 20 is a laboratory-scale, single-use rocking bioreactor designed for precise suspension cell culture and expansion workflows commonly used in biotechnology and bioprocessing applications. It supports controlled cell growth with integrated monitoring and regulation of temperature (2°C–50°C), pH (4.5–8.5 range with control 6.0–8.0), and dissolved oxygen (0–250% air saturation, controlled 0–100%), enabling optimization of upstream processes such as stem cell expansion, CAR-T cell production, vaccine manufacturing, and viral vector biomanufacturing.

Key technical specifications include:

• Rocking platform with adjustable speed (2–40 rpm) and angle (2°–12°) for efficient mixing and gas exchange
• Load capacity: 0.5 to 25 kg to accommodate various bag volumes
• Gas control unit (CBCU) capable of precise CO₂ (0–15%) and O₂ (0–50%) regulation with flow rates from 50 to 1000 mL/min
• Peristaltic pump with flow rates between 0.07–100 mL/min (0.1–144 L/day) for fluid management
• Compatibility with single-use Cellbag bioreactors of 2 L, 10 L, and 20 L sizes, providing working volumes from 300 mL up to 10 L on the Tray 20 platform

The system runs on Unicorn software v7.6 for real-time process control and data logging, supporting scalable, reproducible cell culture processes critical to molecular diagnostics and synthetic biology research. Its modular configuration allows upgrade options for dual-bag operation to increase bioprocess throughput.

This equipment is widely adopted in biomedical engineering and clinical manufacturing environments for applications requiring sterile, controlled culture conditions with flexibility in bioprocess development and cell therapy production.

Features:

• Single-use rocking bioreactor system optimized for live suspension cells
• Integrated measurement and control of critical bioprocess parameters: temperature, pH, dissolved oxygen, CO₂, and O₂
• Supports bioprocesses with precise gas mixing and fluid handling via peristaltic pumps
• Enables consistent and scalable expansion of stem cells, immune cells, and viral vectors
• Compact footprint ideal for laboratory and pilot-scale biomanufacturing
• Validated for stability, safety alarms, and sensor accuracy by extensive in-house testing

This system is essential for researchers and biotech manufacturers aiming for scalable, reproducible bioprocesses in gene editing, cell therapy development, and upstream biomanufacturing workflows. It facilitates streamlined cultivation with minimized contamination risk, making it a core instrument in modern biopharmaceutical production pipelines.

Keywords naturally embedded: rocking bioreactor system, single-use bioreactor, cell expansion system, controlled cell culture, suspension cell culture, bioprocess development, stem cell expansion, CAR-T production, vaccine manufacturing, dissolved oxygen control, pH regulation, gas flow control, molecular diagnostics, synthetic biology research, biomanufacturing equipment, cell therapy manufacturing.