Getinge Applikon my-Control Four-Fold Single-Use Cell Culture Bioreactor System

The Getinge Applikon my-Control four-fold single-use cell culture bioreactor system is a modular platform for parallel mammalian cell culture, process development, screening, and scale-down bioprocessing studies. Applikon Biotechnology is now part of Getinge.

• Configuration: Four independent my-Control bioreactor controllers
• Included hardware:
• 4 × My-Control bioreactor controllers
• 4 × Brushless Stirrer Motor M02.1
• 4 × temperature probes
• 8 × optical fibers for pH and dissolved oxygen measurement
• 4 × heating blankets
• 4 × vessel holders
• 4 × Peltier exhaust condensers
• Laptop computer
• Network switch
• Communication and power cables
• Process inputs: pH, temperature, dissolved oxygen, and agitation
• Gas control: 4 mass flow controllers (MFCs) with specified flow rates of N₂ at 160 mL/min, air at 10 mL/min, O₂ at 40 mL/min, and CO₂ at 40 mL/min
• Liquid handling: 4 variable-speed pumps with a range of 0–200 rpm
• Vessel compatibility: Applikon Appliflex ST 500 mL single-use vessels
• Drive system: Direct drive
• Maximum stirrer speed: 2,000 rpm; 250 rpm with a single-use bioreactor
• Aeration: Air supply through a porous sparger and overlay
• pH control: CO₂ gas combined with an alkali pump
• Dissolved oxygen control: Combined N₂, air, O₂, and agitation control
• Temperature control: Electric heating blankets
• Exhaust condensation: Peltier coolers

The system is suited to parallel cell culture process development, comparison of culture conditions, media and feed screening, bioprocess optimization, and reproducible biotechnology workflows. Its single-use vessel configuration helps reduce cross-contamination risk and avoids cleaning and sterilization between runs.

Consumable vessels and other single-use supplies are not included. The listed system was manufactured in 2024 and underwent functional testing of the power system, peristaltic pumps, agitation motor, temperature probe, optical pH and dissolved oxygen transmitter, heating system, and gas-mixing components.