Shimadzu MCE-202 MultiNA Microchip Electrophoresis System

The Shimadzu MCE-202 MultiNA Microchip Electrophoresis System is a premier tool for the analysis of DNA and RNA sample sizes, offering convenience and cost efficiency akin to agarose gel electrophoresis. It automates the analysis of up to 108 samples, utilizing specialized reagent kits—four for DNA and one for RNA—to ensure high resolution and sensitivity. This system enhances workflows for mutation checks in genome editing and genotype determination. Compatible with 96-well PCR plates and 12/8-strip PCR tubes, it uses quartz microchips with a 23 mm separation channel length and on-chip electrodes. The innovative system includes automatic sample injection, separation buffer replenishment, and chip cleaning.

Operating at a maximum voltage of 1.5 kV with a current of up to 250 μA, the system's analysis cycle time is approximately 80 seconds using four chips. Using LED-excited fluorescence at a 470 nm excitation wavelength, it offers a separation size range from 25 to 12,000 bp for DNA and up to 28S rRNA for RNA, with excellent resolution and size accuracy.

With a required sample volume ranging from 2 to 30 μL, and capable of handling salt concentrations and detection limits effectively, this system ensures precise quantitation results. Its compact dimensions (415 x 545 x 508 mm) and 43 kg weight make it a versatile addition to any laboratory focused on genetic analysis.