Beckman Multisizer 4e B23005 Particle Size Analyzer Coulter Counter with Digital Pulse Processing

The Beckman Multisizer 4e B23005 is a precision particle size analyzer and Coulter Counter designed for detailed particle characterization in biotechnological and clinical research applications. Utilizing patented digital pulse processing technology, this instrument delivers high-resolution sizing data across a broad range from 0.2 to 1600 micrometers. It supports multiple aperture sizes (10–2000 μm) to accommodate diverse particle types including mammalian cells, bacteria, and biochemical particles, facilitating precise counts and sizing critical in molecular diagnostics, bioprocessing workflows, and synthetic biology research.

Powered by electrical zone sensing, the Multisizer 4e accurately detects individual particles in both aqueous and non-aqueous solvents, enhancing its adaptability for biomedical engineering and biomanufacturing process monitoring. The system supports sampling rates up to 10,000 counts per second and can detect as low as 1 particle per ml under optimal conditions, making it essential for live-cell imaging preparations and fluorescence analysis requiring precise particle discrimination.

Equipped with CFR 21 Part 11 compliant software, it ensures rigorous data integrity and audit control suitable for regulated environments in clinical diagnostics and gene editing research labs. The unit includes power and data cables with software, and while calibration is due, it is verified to power on and function properly.

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This analyzer is widely used for biotechnology applications including molecular cloning workflows, biopharmaceutical production pipelines, and particle size measurements crucial in neuroscience and cell imaging studies, providing reliable, high-throughput particle size and count analysis in complex biological and chemical suspensions.