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Molecular Devices ImageXpress Micro Confocal High-Content Imaging System with NIR Laser
Product Description
The Molecular Devices ImageXpress Micro Confocal High-Content Imaging System is a precision spinning disk confocal microscope platform optimized for high-throughput cellular and biological research. Key technical features include:
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Optics and Imaging:
- Dual spinning disk geometry with 60 µm and 42 µm pinholes reducing photobleaching and enabling sharp confocal imaging.
- Andor sCMOS camera for high-sensitivity fluorescence capturing.
- Nikon objectives ranging from 2x/0.10 to 40x/0.60 ELWD for flexible magnification and resolution.
- 4-position automated objective changer and 5-position dichroic plus 8-position emission filter wheels with installed filters (DAPI, FITC, Cy3, TRITC, Texas Red, CY5) support multiplex fluorescence.
- Nikon 100W halogen lamp for brightfield and transmitted light imaging, including a high-contrast diascopic illumination option for non-fluorescent samples.
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Stage and Focus Control:
- Linear encoded voice coil-driven X, Y, Z motorized stages with <25 nm precision for reproducible sample positioning across slides and multiwell plates (1 to 1536 wells).
- High-speed laser autofocus system with integrated image autofocus enhances focus stability during multi-position time-lapse and 3D imaging.
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Light Sources:
- 89 North LDI-NIR laser diode light engine enables near-infrared excitation suitable for advanced fluorescence assays and deep tissue imaging applications.
- 100W Nikon halogen lamp supports transmitted and brightfield illumination.
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Environmental Control for Live-Cell Imaging:
- Maintains physiological temperature (30–40 °C ±0.5 °C), controlled humidity, and atmospheric CO2 conditions (5% or 10% premixed gas) to support long-term, multi-day live-cell time-lapse experiments minimizing sample evaporation.
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Software and Automation:
- Includes MetaXpress 6.7.2 acquisition and analysis software with integrated wizards for time-series, Z-series (3D) capturing, asynchronous kinetics, curve fitting, and advanced transmitted light segmentation.
- Supports customized analysis modules and integration with MetaXpress PowerCore for enhanced throughput screening and phenotypic screening workflows.
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Sample Compatibility and Throughput:
- Compatible with standard slides and microplates from 1-well up to 1536-well formats, both round and flat bottom, enabling high-content screening in drug discovery, cell viability, and 3D culture assays.
- Imaging throughput exceeds >160,000 wells/day for confocal mode and >200,000 wells/day in widefield mode, facilitating large-scale biopharmaceutical compound screening and molecular diagnostics studies.
This system is widely adopted in biotechnology, molecular diagnostics, and synthetic biology research, being critical for bioprocessing applications, gene editing validation, and biomanufacturing pipelines that require high-content, multiparametric cellular analysis. The inclusion of the NIR laser also supports advanced fluorescence assays with reduced background and phototoxicity, essential for live-cell imaging and fluorescence analysis in biomedical engineering and neuroscience applications.
The package includes all necessary components for immediate deployment: instrument unit, power and options controller, installed emission filters, Nikon objectives, illumination arm with halogen lamp, single slide holder, computer with licensed MetaXpress software, and accessories. The system is fully tested for functionality, stage movement, imaging clarity, autofocus, and filter operation, backed by a 120-day US warranty and 60-day international warranty, and is eligible for remote setup and training.
This imaging platform is critical for high-throughput screening, phenotypic assays, and 3D cell culture imaging, combining high resolution, automation, and environmental control tailored for advanced cellular biotechnology workflows and molecular biology research environments requiring reproducible, high-quality confocal imaging data.
Primary keywords: confocal high-content imaging system, spinning disk confocal microscope, multiwell plate imager, live-cell imaging system, fluorescence imaging, high-throughput screening.
Long-tail keywords included: high-content imaging platform for biological and cellular research, essential for molecular cloning workflows, widely adopted in synthetic biology research, critical in biopharmaceutical production pipelines, multiwell plate compatible confocal microscope system, integrated laser autofocus for time-lapse and 3D imaging, environmental control for live-cell time-lapse experiments.
Item Stats
Product details
| Stock | In Stock |
| Brand | Molecular Devices |
| Product Code | 62562 |
| Condition | Pre-Owned |
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