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Molecular Devices ImageXpress Micro Confocal Automated High-Content Imaging System with Spinning Disk Confocal and sCMOS Camera
Product Description
The Molecular Devices ImageXpress Micro Confocal High-Content Imaging System is an advanced automated imaging platform designed for high-throughput and high-resolution cellular analysis. This system integrates dual spinning disk confocal optics with a high-sensitivity Andor Zyla sCMOS camera, enabling superior fluorescence imaging critical for applications in molecular diagnostics, bioprocessing, and synthetic biology research.
Key technical features include:
- Dual spinning disk geometry with 60 µm pinhole and 50 µm slit for confocal optical sectioning and enhanced image contrast.
- Motorized linear encoded voice coil-driven X, Y, and Z stages offering sub-25 nm resolution positioning for precise sample localization and reproducible multiwell plate imaging including 1536-well plates.
- A 4-position automated objective changer loaded with Nikon Plan Apo objectives (4x/0.20, 10x/0.45, 20x/0.75, 40x/0.95) ensuring flexible magnification for detailed cellular and tissue imaging.
- Multi-position dichroic and emission filter wheels with installed filters (DAPI, FITC, TRITC, Texas Red, Cy3, CY5) supporting multi-channel fluorescence detection necessary for multiplexed assays and complex phenotype analysis.
- Lumencor Aura II light engine and Nikon 100W halogen lamp for stable and uniform illumination across a broad fluorescence spectrum.
- Compatibility with diverse samples including glass slides and microplates (round, flat bottom; low to high profile), facilitating workflows from live-cell imaging to high-throughput drug screening.
The system supports essential biotechnology workflows such as live cell time-lapse imaging with controlled environmental conditions (temperature 30–40 °C ±0.5 °C, CO₂ regulation, humidity control) to maintain physiological relevance during long-term experiments. The transmitted light option enables high-contrast imaging of unstained or histochemically labeled samples, complementing fluorescence analysis for comprehensive morphological studies.
The bundled MetaXpress 6.7.2 software suite delivers robust acquisition and offline analysis capabilities, including:
- Time-series and Z-series acquisition and analysis for 3D cellular imaging and kinetic studies.
- Custom Module Editor for bespoke image processing pipelines.
- Transmitted light segmentation and asynchronous kinetics support complex image quantification essential in molecular biology and biopharmaceutical production pipelines.
- Integration with MetaXpress PowerCore software enhances throughput with parallel computing for large dataset processing.
This imaging system is widely adopted in fields such as cell biology, neuroscience, clinical diagnostics, and biomanufacturing. It is particularly valued for applications requiring automated multi-channel fluorescence screening, live cell imaging for gene editing validation, and high-content phenotypic profiling.
Included components:
- Andor Zyla sCMOS camera
- Spinning disk dual disk confocal unit
- Nikon 4x, 10x, 20x, 40x Plan Apo Lambda objectives
- Lumencor Aura II LED light source
- Nikon illumination arm with 100W halogen lamp
- Automated filter wheels with fluorescence filters installed
- Motorized XYZ stage with <25 nm positioning resolution
- MetaXpress 6.7.2 acquisition and analysis software
- Computer workstation with monitor, mouse, keyboard
- Single slide holder and microplate compatibility (up to 1536 well)
- Optional environmental chamber for live cell imaging
This system undergoes comprehensive in-house testing to ensure full operational functionality including autofocus, filter wheel performance, stage precision, and image clarity. It offers critical capabilities for biotechnology research workflows such as molecular cloning assays, synthetic biology imaging, and high-throughput phenotypic screening in drug discovery pipelines.
Ideal for laboratories seeking reliable, high-content confocal imaging systems optimized for multiwell plate assays and live-cell applications in cutting-edge biomedical engineering and molecular diagnostics.
Item Stats
Product details
| Stock | In Stock |
| Brand | Molecular Devices |
| Product Code | 66029 |
| Condition | Pre-Owned |
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