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Teledyne ISCO CombiFlash EZ Prep UV/ELSD Preparative Flash Chromatograph System
Product Description
The Teledyne ISCO CombiFlash EZ Prep UV/ELSD Preparative Flash Chromatograph System is a compact benchtop instrument designed for rapid purification workflows in pharmaceutical research and synthetic biology. It combines flash chromatography and preparative HPLC modes for versatile preparative separation of synthetic organic compounds, natural products, and intermediates at milligram to tens of grams scale.
Key Technical Specifications:
- Flow rate: 5–200 mL/min with ±5% accuracy
- Pressure range: Up to 3500 psi (240 bar) for high-pressure prep HPLC; 200 psi (13.8 bar) for flash operation
- Detection: Variable wavelength UV detector (200–400 nm, ±5 nm increments) combined with built-in ELSD (Evaporative Light Scattering Detector) for compounds with or without chromophores
- Gradient capabilities: Binary gradient programming among four solvents, supporting linear, step, and isocratic gradients with ±3% accuracy
- Pumping system: Dual-head HPLC pumps for precise solvent delivery
- Sample injection: Automated, self-cleaning flash injection valve and Prep HPLC injection valve with loop for reproducible sample introduction
- Gas inlet pressure: 60–70 psig with gas consumption <2.5 SLPM
- Detector temperature control: ELSD drift tube 30–90 °C; spray chamber 10–60 °C, temperature limited to at least 5 °C below ambient
- Dimensions: 17 x 17 x 26.5 inches (43 x 43 x 67 cm)
- Weight: 43.6 kg (96.1 lbs)
- Power requirements: Universal 100–240 VAC, 50/60 Hz
Applications and Research Fields:
- Purification of complex mixtures in biotechnology and molecular diagnostics workflows
- Isolation of synthetic intermediates in medicinal chemistry and gene editing research
- Separation of natural products in bioprocessing and synthetic biology studies
- Preparative-scale sample cleanup essential for biopharmaceutical production pipelines
- Widely used in biotechnology labs focused on organic synthesis, bioactive compound isolation, and molecular cloning
Features Optimized for Biotechnology and Research:
- Dual UV/ELSD detection enables monitoring of diverse compound classes, including those lacking strong UV absorbance common in metabolite profiling
- High-pressure capacity and versatile solvent gradients support complex bioprocessing purification needs
- Automated injection and fraction collection streamline workflows in molecular biology and synthetic biology labs
- Compact footprint fits well in biotechnology laboratories requiring efficient separation systems without large space requirements
Additional Information:
The system is supplied fully functional, tested, and comes with a 120-day warranty in the Continental US and 60 days internationally. Remote setup, training, and technical sales consultation are available. Accessories include intake and waste hoses, power cables, and column bypass tubing; consumables such as columns and racks are sold separately.
This instrument is crucial for biotechnology researchers needing a reliable, dual-mode preparative chromatography platform for compound purification, essential in gene editing, biomanufacturing, and molecular diagnostics workflows. Its integration of flash and preparative HPLC modes with UV and ELSD detectors makes it suitable for a variety of bioprocessing and pharmaceutical applications requiring high throughput and precise fractionation with excellent reproducibility.
Item Stats
Product details
| Stock | In Stock |
| Brand | Teledyne Isco |
| Product Code | 65101 |
| Condition | Pre-Owned |
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