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Teledyne Isco CombiFlash NextGen 300+ Flash Chromatography System with UV and ELSD Detection
Product Description
The Teledyne Isco CombiFlash NextGen 300+ is a versatile flash chromatography system designed for precise and efficient purification workflows, widely used in synthetic organic chemistry, molecular diagnostics, and bioprocessing laboratories. This system integrates a binary gradient solvent delivery system with a variable UV detector (200–400 nm) and an Evaporative Light Scattering Detector (ELSD), enabling detection of both UV-active and non-UV-active compounds critical in biotechnological applications such as synthetic biology and biomanufacturing.
Key technical specifications include:
- Flow rate range: 1–300 mL/min supporting scalable purification volumes
- Maximum pressure: up to 20 bar (300 psi) with user-defined limits ensuring solvent and column integrity
- Gradient control: Four solvent inlets enabling complex binary gradients with ±2% accuracy for reproducible separations
- UV Detection: Variable wavelength from 200 to 400 nm for selective analyte monitoring
- ELSD Detector:
- Gas inlet pressure: 60–70 psig (414–483 kPa)
- Gas consumption: <2.5 SLPM
- Spray chamber temperature range: 10 to 60 °C (minimum guaranteed 5 °C below ambient)
- Drift tube temperature: 30 to 90 °C (maximum 60 °C above ambient)
- Split flow rate: 0.75 mL/min ±10%, minimum flow rate 5 mL/min
- Automation: Automated fraction collection with RFID rack and column detection, precise fraction arm positioning
- Interface: Intuitive touch screen and manual control for flexible operation in research and clinical diagnostic workflows
- Dimensions & Weight: 66 x 36 x 43 cm (H x W x D), 33.6 kg (74 lbs)
- Power Requirements: 100–240 VAC, 50/60 Hz, 2A
This chromatographic platform is essential for applications such as purification of synthetic organic intermediates, isolation of target molecules from reaction matrices, and separation of compounds lacking chromophores using ELSD detection. The system’s robust fluidics, including check valves and solvent filters, ensure stable flow and minimal gradient drift, crucial for reproducible biopharmaceutical compound separation and downstream analysis workflows.
Additional benefits include:
- Extensive in-house testing for power, calibration, fraction arm movement, solvent gradient performance, UV and ELSD detector validation
- Remote instrument setup and training to facilitate rapid integration into biotech and molecular biology laboratories
- Warranty and after-sales technical support available, supporting critical infrastructure in biotechnology research and development
The CombiFlash NextGen 300+ supports researchers in gene editing, molecular cloning, synthetic biology, and molecular diagnostics by providing reliable and accurate compound purification, indispensable for advanced bioprocessing and analytical workflows.
Keywords and phrases naturally incorporated: flash chromatography system, gradient purification system, UV and ELSD detectors, bioprocessing, synthetic biology research, molecular diagnostics, automated fraction collector, biopharmaceutical production pipelines, non-UV-active compound separation, chromatography gradient accuracy.
Item Stats
Product details
| Stock | In Stock |
| Brand | Teledyne Isco |
| Product Code | SM101894-2R |
| Condition | Pre-Owned |
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