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Waters ACQUITY UPLC H-Class PLUS Bio System with PDA and FLR Detectors – 2021 Model
Product Description
The Waters ACQUITY UPLC H-Class PLUS Bio System is a state-of-the-art ultra performance liquid chromatography platform engineered for precise and robust bioseparations in biotechnology and molecular diagnostics. This 2021 model includes integrated photodiode array (PDA) and fluorescence (FLR) detectors, facilitating complementary UV-Vis and fluorescence detection suitable for detailed biomolecule analysis such as monoclonal antibody characterization, glycan profiling, and peptide mapping.
Key system components and specifications include:
- BioQuaternary Solvent Manager (ACQ-QSM, REF 186015081):
- Capable of blending up to four solvents with quaternary gradient formation using low-pressure mixing.
- Integrated four-chamber vacuum degassing and optional six-port solvent select valve for expanded solvent selection.
- Features Auto-Blend Plus™ technology for automated online pH, ionic strength, and organic modifier blending.
- Eleven programmable gradient curves for flexible solvent programming.
- BioSample Manager (ACQ-FTN-H, REF 186015086):
- Injection volume range: 0.1–10 µL standard, extendable up to 1000 µL with optional loops.
- Equipped with 50 µL sample loop; exceptional injection precision (≤0.25% RSD across volumes).
- Supports various sample plate formats (96, 384 microtiter plates, vials, microcentrifuge tubes), with capacity up to 768 samples.
- Temperature control from 4.0 to 40.0 °C with ±0.5 °C accuracy, ensuring sample integrity.
- Integrated needle wash and minimal carryover (≤0.002%) optimize reproducibility.
- PDA Detector (REF 186015032):
- Detection range: 190–500 nm; optical resolution 1.2 nm; flow cell volume 500 nL.
- Max pressure 1000 psi; includes deuterium lamp light source and intelligent flow cell technology.
- FLR Detector (REF 186015029):
- Excitation: 200–890 nm; Emission: 210–900 nm with 20 nm bandwidth.
- Sensitivity >1000 S/N; flow cell volume <2 µL; max pressure 500 psi.
- Column Manager (REF 186015043 & 186015049):
- Supports up to four columns with programmable switching valves.
- Temperature range 4–90 °C with two independent heat/cool zones per module, providing precise column temperature control.
The system is optimized for biocompatible workflows featuring inert flow path materials to reduce sample adsorption, crucial for biomolecule analysis and biopharmaceutical applications. Its high sensitivity, accurate solvent delivery, and temperature control ensure reproducible separations vital for bioprocessing, synthetic biology, and molecular diagnostics workflows.
The package includes Empower data acquisition software, all necessary intercommunication cables, solvent tray, and power cords. Fully tested, serviced, and minimally used with warranty and technical support provided.
This UPLC system is essential for researchers in biotechnology, molecular biology, clinical diagnostics, biomanufacturing, and synthetic biology, supporting complex assays such as live-cell compatible biocompatible separations, fluorescence-based biomolecule detection, and gene editing quality control. Its reliable gradient control and combination of PDA and FLR detectors make it a versatile platform widely adopted in advanced biomedical and biopharmaceutical production pipelines.
Primary Keywords: UPLC system, bioseparation, PDA detector, FLR detector, quaternary solvent manager, molecular diagnostics.
Long-tail Phrases: essential for molecular cloning workflows, widely adopted in synthetic biology research, critical in biopharmaceutical production pipelines, fluorescence-based biomolecule detection in biotechnology, high-sensitivity bioanalytical UHPLC for monoclonal antibody characterization.
Item Stats
Product details
| Stock | In Stock |
| Brand | Waters |
| Product Code | 68359 |
| Condition | Pre-Owned |
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