Teledyne ISCO CombiFlash EZ Prep UV-VIS Preparative Flash Chromatography System

The Teledyne ISCO CombiFlash EZ Prep UV-VIS Preparative Flash Chromatography System integrates prep-scale flash and preparative HPLC modes, designed for efficient compound purification in organic synthesis, natural products isolation, and medicinal chemistry scale-up. Equipped with dual piston gradient pumps offering a wide flow rate range of 5–200 mL/min and pressure capability up to 3500 psi (240 bar) for high-pressure operations, this system supports rapid purification even with backpressure-sensitive compounds.

The system features a UV-VIS detector configurable across 200 to 800 nm in 5 nm increments, enabling selective detection and precise fraction triggering critical for molecular diagnostics, bioprocessing, and biomanufacturing workflows. It supports a binary solvent gradient from four solvents with programmable linear, step, and isocratic gradients featuring ±3% accuracy, essential for optimized separation of closely related analogs or isomers.

Additional components include collection racks, intake and waste hoses, and software-controlled operation facilitating high reproducibility and seamless integration in biotechnology laboratories focused on synthetic biology and gene editing applications requiring scalable purification of complex biomolecules. The system’s pressure-rated hardware ensures stability and prevents gradient drift, baseline instability, or fraction cross-contamination—a necessity in clinical diagnostics and cell imaging research workflows.

Technical specifications:

This unit is validated with extensive servicing, calibration of pumps and UV detection, and comes with remote setup, training options, and warranty coverage. Its robust design and adaptability make it widely adopted in biotechnology research environments, particularly essential for molecular cloning workflows and biopharmaceutical production pipelines where high purity and reproducibility are critical.