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Precision NanoSystems NanoAssemblr Blaze Lipid Nanoparticle Formulation System for Preclinical and GMP Bioprocess Development

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Product Description

The Precision NanoSystems NanoAssemblr Blaze system is a sophisticated lipid nanoparticle formulation system designed to optimize the development and scale-up of LNPs relevant to biotechnology, molecular diagnostics, and gene editing workflows. Its NxGen™ technology ensures precise and reproducible mixing conditions by controlling flow rates, facilitating consistent nanoparticle size and composition critical in synthetic biology and bioprocessing applications.

Key features include:

  • Flexible volume capacity: Choose the Blaze model for low-volume formulations up to 1 L or upgrade to the Blaze+ for high-volume processing up to 10 L, supporting toxicity assessments, stability testing, and large animal studies.
  • Closed system environment: The Blaze+ system supports external vessel integration and software upgrades to enable sterile, GMP-compliant manufacturing conditions, reducing contamination risks during scale-up.
  • Process development focus: Supports early CMC (Chemistry, Manufacturing, and Controls) studies and large-scale protocol optimization for upstream and downstream operations, including tangential flow filtration (TFF) and sterile fill/finish steps.
  • Efficient clinical process verification: Streamlines preclinical manufacturing by shortening run times and simplifying setup, saving resources while verifying critical process parameters (CPPs).
  • Seamless scale-up compatibility: Facilitates technology transfer to the NanoAssemblr commercial formulation system, bridging preclinical research to cGMP biomanufacturing necessary for biopharmaceutical production pipelines.

This system is widely used in biomedical engineering, gene therapy research, and nanomedicine fields, making it essential for molecular cloning workflows involving lipid nanoparticle vectors and gene editing delivery technologies. It caters to research professionals engaged in biomanufacturing scale-up and synthetic biology applications requiring reproducible particle formation and controlled bioprocess conditions.


Item Stats

Status
For Sale
State
used
Brand
Precision Nanosystems
Model
NanoAssemblr Blaze
Location
Woonsocket - United States

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