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Thermo Scientific Q Exactive HF Advanced Quadrupole Orbitrap LC-MS/MS High-Resolution Mass Spectrometer
Product Description
The Thermo Scientific Q Exactive HF is a benchtop high-resolution mass spectrometer designed for advanced liquid chromatography-mass spectrometry (LC-MS/MS) workflows. Featuring an ultra-high-field Orbitrap analyzer, it delivers exceptional resolving power of 240,000 FWHM at m/z 200 and rapid scan speeds up to 18 Hz, critical for high-throughput proteomics and small molecule characterization. The instrument incorporates Advanced Quadrupole Technology for enhanced precursor ion isolation, supporting quantitative workflows including Selected Ion Monitoring (SIM), Parallel Reaction Monitoring (PRM), and Data-Independent Acquisition (DIA), widely used in molecular diagnostics and biopharmaceutical research.
Key technical specifications include:
- Mass range: 50 to 6,000 m/z for broad analyte detection
- Mass accuracy: Sub-ppm with internal calibration (<1 ppm RMS) ensuring precise molecular mass determination
- Sensitivity: Capable of detecting 500 fg buspirone on-column with high signal-to-noise ratio (S/N 100:1)
- Dynamic range exceeding 5000:1 for reliable quantification of low-abundance biomolecules
- Rapid polarity switching (<1 second) for versatile analysis in positive and negative modes
- Compatibility with EASY-Spray and Nanospray Flex ion sources enhancing sensitivity and robustness for peptide and protein analysis
- Inclusion of Higher-Energy Collisional Dissociation (HCD) enables effective peptide fragmentation critical to proteomics and synthetic biology workflows
This system is integral to bioprocessing, gene editing validation, and molecular cloning applications, providing high-confidence, reproducible data essential in cutting-edge biotechnology and pharmaceutical development pipelines. Though the unit requires calibration and does not include system PC or software licenses, it remains in excellent operational condition with minor cosmetic wear. Ideal for comprehensive proteomic research, small molecule quantitation, and detailed intact protein analysis in biomedical engineering and clinical diagnostics contexts.
Item Stats
Product details
| make | Thermo Scientific |
| hertz | 50Hz/60Hz |
| model | Q EXACTIVE HF |
| serial | 05061L |
| weight | 400.0 Lb |
| voltage | 230V |
| includes | Power cord included | |
| warranty | 30-Day Warranty On Part |
| dimensions | 30.0in x 34.0in x 37.0in |
| shipping_type | Freight |
| item_condition | Good |
| manufacturing_date | Does Not Apply |
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Northeastern UniversityFrom €42,165.52*ex. VAT
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