Nikon Ti2-E PFS N-SIM Super-Resolution Inverted Motorized Microscope with Dual Fluorescence Illumination

The Nikon Ti2-E PFS N-SIM is an advanced super-resolution inverted motorized microscope designed for high-precision biomedical imaging and biotechnology research. It integrates dual fluorescence illumination combining a laser-based structured illumination (SIM) system and a widefield LED fluorescence source, ideal for quantitative multi-channel fluorescence and live-cell imaging workflows.

Key technical features include:

Additional configurable options allow customization to fit specific research needs: addition of phase contrast, DIC or polarization modules; high-NA Nikon apochromat objectives; expanded filter sets compatible with diverse fluorophores such as DAPI, FITC, Texas Red, and Cy5; upgraded high-end CCD, EMCCD cameras; and enhanced illumination sources (Xenon, Metal Halide, or LED).

This system suits a broad range of laboratory applications, including:

The N-SIM module, while included, requires professional setup by Nikon technicians for full super-resolution capability. The microscope is fully serviced, field-tested for distortion and fluorescence intensity uniformity, and shipped with a warranty and optional training. It is widely adopted in advanced biotechnological imaging workflows where precision and automation are critical.

This Nikon Ti2-E system enables researchers, biotechnologists, and clinical professionals to conduct complex multi-channel fluorescence experiments with automated controls and high fidelity, supporting rigorous molecular diagnostics, gene editing analyses, and bioprocessing imaging pipelines.