Nikon Diaphot TMD Inverted Phase-Contrast Microscope with Leica Mechanical Micromanipulators (40X-400X)

The Nikon Diaphot TMD is a robust inverted phase-contrast microscope engineered for advanced life science research, particularly live-cell imaging and tissue culture observations. It features an optically advanced short light path system integrating a focusable Bertrand lens, photomask reticle, and dark slide within its phase-contrast turret assembly. The microscope supports magnifications from 40X to 400X using three Plan objectives (4X, 10X, and 40X) combined with CFWN 10X eyepieces.

Key technical specifications include:

This microscope is equipped with two Leica mechanical micromanipulators, essential tools in biotechnology and neuroscience research for applications like patch clamping, microsurgery, and cellular manipulation. The Leica units offer continuously selectable gear reduction, enabling backlash-free, precise translation of operator hand movements to micro-tools, matching the microscope’s magnification levels. This setup is widely adopted in synthetic biology research and molecular cloning workflows requiring spatial accuracy and stability.

Additional accessories include measuring syringes with tubing and a support stand with clamp, enhancing its utility in controlled experimental setups. The Nikon Diaphot TMD system is critical in biomedical engineering and clinical diagnostics, supporting fluorescence analysis and phase-contrast imaging essential for molecular diagnostics and live-cell observation.

This integrated microscopy platform is well-suited for researchers and scientists focusing on bioprocessing, gene editing, and biopharmaceutical production pipelines, delivering precise, high-resolution imaging and manipulation capabilities tailored to advanced biotechnology applications.