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Molecular Devices ImageXpress Micro Confocal HT.ai High-Content Confocal Imaging System with Automation, Environmental Control, and Water Immersion Optics
Product Description
The Molecular Devices ImageXpress Micro Confocal HT.ai is an advanced high-content imaging system engineered for quantitative confocal fluorescence and transmitted light microscopy with fully integrated automation and environmental control, essential for biotechnology, molecular diagnostics, and live-cell imaging applications. It supports multiplexed fluorescence assays and 3D imaging workflows critical in synthetic biology research and biopharmaceutical production pipelines.
Key technical features include:
- Confocal Imaging System: Dual spinning disk with 50 µm slit and 60 µm pinhole geometry; laser-based optical sectioning using the 89 North LDI-NIR EX light engine (Class 4 laser) at wavelengths 405, 445, 470, 520, 555, 640, 730 nm plus 100W Nikon halogen illumination for transmitted light.
- Imaging Optics: Nikon Plan Apo objectives (4x/0.20, 10x/0.45, 20x/0.95 water immersion, 40x/1.15 water immersion) with a 4-position automated objective changer, high numerical aperture water immersion objectives for enhanced resolution in aqueous 3D biological samples.
- Automated Sample Handling: Brooks PreciseFlex 400 robotic arm integrated with Biosero Green Button Go software for unattended multi-plate workflows, supporting slides up to 1536-well microplates with precise robotic positioning (10 µm resolution, ±0.090 mm repeatability).
- Environmental Control: FC-9 Gas Mixer for live-cell time-lapse imaging providing CO₂ control (5-10%), humidity regulation, and temperature stability (30-40°C ±0.5°C), minimizing sample evaporation during long-term experiments.
- Multi-Channel Fluorescence Setup: Installed emission filters for DAPI, FITC, CFP, Texas Red, CY5, CY7, YFP; 5-position dichroic and 8-position emission filter wheels enable multiplexed fluorescence detection.
- Software: MetaXpress 6.7.2 for acquisition and offline image analysis, including time-series, Z-series acquisition and analysis, asynchronous kinetics, and transmitted light segmentation modules, supporting workflows in molecular cloning, cell phenotyping, and neuroimaging applications.
The system enables:
- High-throughput, high-content confocal imaging and phenotypic screening (>160,000 wells/day confocal imaging).
- Versatile sample compatibility for live or fixed cells, spheroids, organoids, and complex tissue models.
- Automated multi-channel imaging with high-speed laser autofocus and precise XYZ motorized stage control (<25 nm resolution).
- Transmitted light imaging capability for label-free morphological visualization complementing fluorescence assays.
This platform is widely adopted for biomedical engineering, clinical diagnostics, and bioprocessing workflows where automated, reproducible, high-resolution imaging of biological specimens is critical. The water immersion capability and environmental controls make it particularly suited for live-cell and 3D tissue imaging in biotechnological and pharmaceutical research.
In summary, the ImageXpress Micro Confocal HT.ai system is a fully integrated, automated confocal high-content imaging solution optimized for multiplexed fluorescence assays, live-cell imaging, and biomanufacturing research workflows requiring environmental control, robotic sample handling, and high-resolution water-immersion optics.
Item Stats
Product details
| Stock | In Stock |
| Brand | Molecular Devices |
| Product Code | 64366 |
| Condition | Pre-Owned |
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