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Leica DMi8 THUNDER Imager Motorized Inverted Fluorescence Microscope with Adaptive Focus Control
Product Description
The Leica DMi8 THUNDER Imager is a motorized inverted fluorescence microscope optimized for advanced widefield fluorescence imaging and live-cell applications. It integrates Leica’s proprietary THUNDER computational clearing technology to enhance image contrast by removing out-of-focus haze in real time, making it widely adopted in biotechnology, including live-cell fluorescence imaging, 3D cell culture visualization, and molecular diagnostics.
Key technical features include:
- Inverted research microscope design supporting brightfield and fluorescence microscopy with options for phase contrast, DIC, and polarization.
- Fully motorized platform with automated control of XY stage, condenser, objective turret (6-position), and fluorescence components for precise and reproducible sample positioning.
- Adaptive Focus Control (AFC) maintains stable focus and enables automated Z-stack acquisitions.
- Fluorescence illumination via Lumencor LED5 Light Engine with motorized 8-position filter cube turret and Leica standard DFT51011 filter sets, supporting multi-channel fluorescence workflows.
- High-contrast, high-resolution imaging through Leica HC Plan Fluotar objectives (5x to 40x) with motorized objective turret.
- Motorized 7-position condenser (S28 0.55 NA) and tiltable transmitted LED brightfield illumination.
- Equipped with a Leica K5 sCMOS camera and LAS X software for advanced acquisition modes including time lapse, multi-channel, Z-control, 3D imaging, and THUNDER OTF.
- Motorized XY scanning stage (Marzhauser), joystick control for automated large area and multi-position imaging.
THUNDER Imaging Technology:
- Uses GPU-accelerated Computational Clearing (CC) to suppress out-of-focus light for sharper images in thick biological specimens such as tissue sections and organoids.
- Enables real-time image enhancement without need for post-processing.
- Enhances signal-to-background ratio, critical for detecting weak or low-intensity fluorophores in molecular biology and synthetic biology research.
- Optimized for live-cell imaging and high-throughput fluorescence workflows with minimal phototoxicity.
Applications:
- Essential for biotechnology and biomedical engineering workflows including stem cell research, developmental biology, drug discovery, and quantitative fluorescence analysis.
- Widely used in live-cell fluorescence imaging, time-lapse studies, multi-channel fluorescence acquisition, 3D imaging of organoids, and neuroscience research.
- Suitable for imaging diverse sample formats: slides, Petri dishes, microplates.
Customizability and Support:
- Custom configurations available to add advanced fluorescence filters, higher magnification or apochromat objectives, and alternative camera options (CCD, EMCCD).
- Comprehensive warranty coverage with remote or in-person training and expert technical consultation ensures operational reliability.
- Meticulous pre-shipment service includes optics cleaning, fluorescence intensity verification at sample plane, and full PM on mechanical and motorized components.
- Extensive support for biopharma and academic research facilities with on-site installation options in select regions.
This microscope delivers precision and automation critical for modern molecular diagnostics and bioprocessing imaging workflows, making it a robust platform for complex fluorescence imaging tasks in biotechnology and clinical research settings.
Item Stats
Product details
| Stock | In Stock |
| Brand | Leica |
| Product Code | 66267 |
| Condition | Pre-Owned |
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