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Revvity EnVision 2105-0020 Multimode Microplate Reader with AlphaScreen Laser and Ultra-Sensitive Luminescence Detection

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Product Description

The Revvity EnVision 2105-0020 is a versatile multimode microplate reader designed for advanced biotechnology, molecular diagnostics, and high-throughput screening applications. It integrates multiple detection technologies to support a wide range of assays essential in bioprocessing, gene editing, and synthetic biology research.

Key Features and Technical Specifications:

  • Detection Modes: Absorbance (ABS), Luminescence (LUM), Fluorescence Intensity (FL), Fluorescence Polarization (FP), Time-Resolved Fluorescence (TRF), TR-FRET (LANCE), and AlphaScreen (filter dependent)
  • Detectors: Photodiode for absorbance; Photomultiplier Tubes (PMTs) for fluorescence, luminescence, TRF, and Alpha mode, ensuring ultra-sensitive detection critical in molecular cloning workflows
  • Light Sources: Broad-spectrum Xenon flash lamp and dedicated AlphaScreen laser for Alpha-based assays, supporting fluorescence and luminescence excitation across 230–1000 nm
  • Optics: Filter-based optical system with multiple precision optical filters and mirrors; full aperture set optimizes readings for 96-, 384-, and 1536-well plates including low-volume and low-profile formats
  • Sensitivity:
    • Absorbance accuracy < 2% at 2 OD with precision < 0.1%
    • Fluorescence intensity sensitivity < 4 pM fluorescein for 96-well plates
    • Luminescence sensitivity < 75 pM ATP per 96-well
    • AlphaScreen sensitivity < 100 amol for 384-well plates
    • Fluorescence polarization precision < 3 mP for fluorescein assays
  • Plate Compatibility: Supports from 1- to 1536-well microplates, enabling applications from standard ELISAs to high-density high-throughput screening (HTS) critical in biomanufacturing and biomedical engineering
  • Shaking Options: Linear, orbital, and dual-orbital plate shaking for enhanced assay mixing
  • Reading Modes: Top and bottom reading capabilities with barcode scanner and plate height sensor facilitate robust assay setup and monitoring
  • Software: Includes EnVision Manager software (Version 1.14.3049.1642) enabling comprehensive control and data acquisition for multiplex assay workflows

Application Areas:

  • Enzyme-linked immunosorbent assays (ELISA) and absorbance-based assays
  • Reporter gene assays including luciferase and fluorescence for gene expression studies
  • Protein-protein interactions using TR-FRET and fluorescence polarization, essential for drug discovery and synthetic biology research
  • Receptor binding and cell viability assays in biomedical and clinical research
  • AlphaScreen technology for sensitive biomolecular interaction detection in molecular diagnostics and bioprocess monitoring
  • High-throughput screening for compound libraries in biotechnology and pharmaceutical development

This instrument’s combination of ultra-sensitive luminescence and AlphaScreen laser detection makes it widely adopted in synthetic biology and molecular cloning workflows, providing reliable, high-sensitivity data for biotechnology professionals.

Additional Notes:

  • Comes new in original packaging with manufacturer warranty and remote instrument setup/training options available
  • Compatible with various optical filter sets and mirror modules, configurable for specific assay needs
  • Installation, technical sales consultation, and after-sales support are provided, ensuring seamless integration into research laboratories focused on molecular diagnostics and biomanufacturing

The Revvity EnVision 2105-0020 is a critical tool for research laboratories requiring a single platform for diverse assay types, particularly valuable in live-cell imaging, fluorescence analysis, and biopharmaceutical production pipelines.


Item Stats

Status
For Sale
State
used
Brand
Perkin Elmer
Model
EnVision 2105-0020
Location
Walpole - United States

Product details

StockIn Stock
BrandPerkin Elmer
Product Code68195
ConditionNew

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