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The Leica RM2125RT Manual Rotary Microtome is a precision instrument designed for routine tissue sectioning in histology, pathology, and biomedical research applications. It enables researchers to produce consistent paraffin-embedded tissue sections with a thickness range from 0.5 to 60 µm, adjustable in fine increments (0–2 µm in 0.5 µm steps, 2–10 µm in 1 µm steps, 10–20 µm in 2 µm steps, and 20–60 µm in 5 µm steps), supporting diverse specimen preparation needs in molecular diagnostics and biotechnology workflows.
Key features include:
This microtome’s compatibility with standard accessories and its robust mechanical design make it widely adopted in clinical diagnostics, biomedical engineering, and research fields requiring high-quality histological sections. It is critical for workflows in gene editing and biomanufacturing, where reliable tissue preparation impacts downstream analysis such as fluorescence microscopy and live-cell imaging.
Dimensions are 19 x 19 x 12 inches, with a weight of 64 lbs, suitable for benchtop laboratory setups. Included components are an adjustable blade holder mount, user manual, and standard warranty coverage.
The Leica RM2125RT is a preferred choice for laboratories demanding precise, consistent microtomy with adaptable section thickness control, optimizing tissue integrity for downstream histopathological and molecular biology analyses.
| Section thickness setting | 0.5 – 60 µm from 0 – 2 µm in 0.5 µm steps from 2 – 10 µm in 1 µm steps from 10 – 20 µm in 2 µm steps from 20 – 60 µm in 5 µm steps |
| Trimming thickness | 10 μm, 50 μm |
| Section thickness indication | visual display |
| Coarse feed | manual, via coarse feed wheel |
| Horizontal specimen feed | approx. 28 mm |
| Vertical specimen stroke length | 60 mm (+/– 1 mm) |
| Specimen orientation (x/y) | 8° |
| Specimen retraction | 220 μm |
| Dimensions | 19x19x12” |
| Weight | 64 lbs |
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