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Cytiva Pall iCELLis Nano 3-Fold Single-Use Fixed-Bed Bioreactor System

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Product Description

The Cytiva Pall iCELLis Nano 3-Fold Single-Use Fixed-Bed Bioreactor System is designed for small to moderate-scale bioprocessing involving adherent cell cultures in biotechnology and molecular diagnostics. This triple-capacity system enables parallel bioreactor runs with flexible fixed-bed surface areas ranging from 0.5 to 4 m². It features:

  • Fixed-bed configurations: 11 cm diameter with configurable bed heights of 2, 4, or 10 cm.
  • Agitation control: Magnetic drive impeller adjustable from 100 to 1500 rpm ensures gentle mixing to maintain optimal cell growth.
  • In-line process analytics: Supports pH, dissolved oxygen (DO), temperature, and optional biomass sensors for real-time monitoring critical in molecular biology and biomanufacturing workflows.
  • Control architecture: Utilizes the mPath Control Tower and PallLink software v1.5.1 for automated process management and data acquisition.
  • Gas handling: Six pre-calibrated thermal mass flow controllers (TMFCs) provide precise gas mixing (N₂, O₂, CO₂, air) with flow rates up to 1000 mL/min per gas, enabling fine control of cell culture environments essential for viral vector production and cell-based research.
  • Temperature control: Peltier element-based heating with reusable PT100 sensor allows stable culturing between 20°C and 40°C.
  • Pumping system: Includes one fixed-speed base addition pump and two variable-speed perfusion pumps to enable nutrient supply and waste removal in continuous culture applications.
  • Physical dimensions: Controller measures 23 × 60 × 45 cm, docking stations measure 34 × 36 × 29 cm; weights are 20 kg and 6.7 kg respectively, facilitating compact laboratory integration.

This system is widely adopted in biopharmaceutical production pipelines including viral vaccine manufacturing (influenza, measles), gene therapy vector production (AAV, lentivirus), monoclonal antibody development, and bioprocess optimization in synthetic biology and molecular cloning workflows. The single-use design reduces contamination risk and simplifies scale-up processes.

Note: Disposable bioreactor vessels and single-use sensors are not included but are required for operation. Comprehensive warranty, technical support, and on-site or remote training options are provided, making it a reliable choice for university research labs and industrial bioprocessing facilities.

This system’s precise gas control, inline sensor integration, and modular configuration make it critical equipment for live-cell imaging studies, fluorescence analysis in cell cultures, and advanced bioprocess engineering in biotechnology and clinical diagnostics.


Item Stats

Status
For Sale
State
used
Brand
Pall
Model
iCELLis Nano Single-Use Fixed-Bed Bioreactor System, 3-Fold
Location
Walpole - United States

Product details

StockIn Stock
BrandPall
Product CodeSM101463-3F
ConditionPre-Owned

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