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Covaris LE220-plus Focused Ultrasonicator with Integrated Water Conditioning System

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Product Description

The Covaris LE220-plus Focused Ultrasonicator is an advanced benchtop acoustic shearing system designed for reproducible, high-throughput DNA and RNA fragmentation essential in molecular diagnostics, next-generation sequencing (NGS) library preparation, and chromatin shearing for ChIP-Seq applications. This instrument integrates proprietary Adaptive Focused Acoustics (AFA) technology, delivering uniform, non-contact acoustic energy to samples, thereby minimizing cross-contamination and ensuring precise shearing results across multiple sample formats.

Key Technical Specifications:

  • Treatment Power: 0.1 to 250 Watts Average Incident Power, up to 500 Watts Peak Incident Power
  • Sample Processing Capacity: 1 to 8 samples in parallel, recommended batch size 8 to 96 samples
  • Sample Volume Range: 5 to 500 µL, compatible with individual microTUBEs, 8-strip microTUBE racks, 96-well microTUBE plates, oneTUBE-10 AFA plates, miniTUBEs, and milliTUBEs
  • Temperature Control: Integrated Water Conditioning System (WCS) enabling water bath temperature range from 5 to 40 °C for precise, controlled sonication conditions
  • Physical Dimensions: 24" (W) x 30" (D) x 19" (H) | 61 x 76 x 48 cm
  • Power Requirements: 100-240V, 50-60Hz, 500VA Max

The integrated Water Conditioning System (WCS) ensures stable temperature regulation critical for reproducible acoustic shearing workflows in bioprocessing and synthetic biology research. The system includes a solid-state chiller and operates with SonoLab 10 software for precise control and automation.

This ultrasonicator supports a broad range of sample holders and consumables, enhancing its versatility across genomics and molecular biology laboratories focused on gene editing, biomanufacturing, and molecular cloning workflows. It is widely adopted in biotechnology for DNA fragmentation, cell lysis, and FFPE tissue sample processing, offering an essential tool in biopharmaceutical production pipelines.

Operational Features:

  • Automated high-throughput sample processing streamlining NGS library preparation
  • Compatible with microplate and tube formats used in molecular biology and clinical diagnostics
  • Safety features include door lock and AutoFill functions to maintain consistent sonication conditions
  • Robust construction designed for integration into automated workflows and manual processing labs

This pre-owned unit is fully tested, serviced, and includes a warranty with remote setup and training options. It is a reliable solution for researchers seeking a high-precision, scalable shearing instrument critical for advanced biotechnological applications.

Keywords: acoustic shearing system, DNA shearing, focused ultrasonicator, next-generation sequencing prep, molecular diagnostics, bioprocessing instrumentation, synthetic biology tools, High-throughput sonication, Covaris LE220-plus, water conditioning sonicator, chromatin shearing.


Item Stats

Status
For Sale
State
used
Brand
Location
Walpole - United States

Product details

StockIn Stock
BrandCovaris
Product CodeSM101234-LE220P
ConditionPre-Owned

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From €8,547.70*ex. VAT

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