Roche LightCycler 480 II 96-Well Real-Time PCR System for Genotyping and Gene Expression Analysis

The Roche LightCycler 480 II PCR System 96-Well is a high-throughput, plate-based real-time PCR instrument designed for advanced molecular diagnostics, genotyping, and gene-expression studies. This automated genomic research platform supports a broad range of fluorescent dyes and probe formats, facilitating SNP analysis and quantitative PCR with high sensitivity and dynamic range (1 to 10^8 copies/well).

Key technical features include:

This system meets export control guidelines and supports compliance with 21 CFR Part 11, essential for clinical diagnostics and regulated biotechnology research applications. Although currently sold AS-IS requiring repair of the lamp module, the LightCycler 480 II holds significant value for users skilled in instrument maintenance or those sourcing parts for molecular biology laboratories.

Its precision and versatility make it widely adopted in biotechnology fields such as synthetic biology, molecular cloning, and biopharmaceutical production pipelines—critical for workflows involving gene editing and molecular diagnostics. The system's comprehensive software, user manuals, and power accessories are included, enabling integration into laboratories focused on cell imaging, fluorescence analysis, and biomedical engineering.

This instrument, manufactured by Roche in the U.S.A., supports rigorous applications in biotechnology research and clinical genomics, making it a pivotal tool for researchers conducting high-throughput quantitative PCR assays and complex genotyping studies.