Thermo Scientific LTQ Orbitrap XL & LTQ XL ETD Hybrid High-Resolution Mass Spectrometer

The Thermo Scientific LTQ Orbitrap XL & LTQ XL with ETD is a high-resolution, high-sensitivity hybrid mass spectrometer integrating the linear ion trap (LTQ) with Orbitrap technology and Electron Transfer Dissociation (ETD) ionization capabilities. This system enables detailed analysis of complex proteins and small molecules, making it essential for advanced biochemical research and molecular diagnostics workflows in biotechnology, proteomics, and synthetic biology.

This preowned unit, manufactured in Germany, powers on but requires calibration and validation due to incomplete testing and absence of control software. Minor cosmetic defects and mechanical issues were noted, including unexpected power shutdown during pump initialization. It does not include computer or power/data cables.

Widely used in biopharmaceutical production pipelines and molecular diagnostics laboratories, this mass spectrometer supports detailed protein characterization, including post-translational modification mapping, critical in bioprocessing and gene editing research. Its combined Orbitrap and LTQ ETD functionalities optimize workflows for live-cell imaging correlates, fluorescence analysis, and advanced cellular proteomics.

This system is highly applicable for researchers requiring accurate mass measurements and fragmentation techniques essential for molecular cloning workflows, synthetic biology research, and clinical diagnostics. Proper installation, calibration, and software integration are necessary to ensure optimal performance and analytical accuracy in demanding biotechnology and clinical research environments.