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Miltenyi Biotec CliniMACS Prodigy Automated Cell Processing System for GMP Cell Manufacturing
Product Description
The Miltenyi Biotec CliniMACS Prodigy Automated Cell Processing System is a compact, closed-system platform designed to automate complex cell manufacturing workflows essential for molecular diagnostics, gene therapy, and bioprocessing. Engineered for compliance with GMP standards, this instrument integrates multiple cell processing steps including:
- Magnetic cell separation for T cells, NK cells, and stem cells using the magnetic separation column
- Automated cell washing, density gradient centrifugation, and cell activation within a temperature-controlled CentriCult Unit (4°C to 38°C)
- Genetic modification via viral transduction and fluorescent antibody labeling for in-depth cell characterization
- Cell expansion and differentiation, supporting both suspension and adherent cell cultures
- Integrated IPC/QC sampling pouches for sterile sample removal ensuring process validation
- Precision fluid handling via a peristaltic pump operating between 2-400 ml/min with pinch valves controlling fluid paths
- Gas mix unit providing controlled atmosphere with CO2, compressed air, and N2 for optimal cell cultivation conditions
The system’s 10.1” full-color touchscreen controller includes preinstalled software supporting over 300 customizable protocols currently utilized in more than 150 clinical trials. This allows scientists and biotechnology professionals to streamline workflows, minimize human error, and scale processes from research-grade cell sorting to commercial biomanufacturing.
Additional technical specifications: centrifugation up to 2500 rpm (400 x g), microscope camera magnification up to 400x, and compatibility with starting materials such as leukapheresis, bone marrow, and cryopreserved pluripotent stem cells. The device supports seamless network connectivity for data export and remote monitoring, integrating with laboratory information management systems common in biomedical engineering and cell therapy manufacturing.
Manufactured in Germany, the CliniMACS Prodigy measures 29x16x19 inches, weighs 155 lbs, and operates on 100-240V, 50/60Hz power supplies. It is widely recognized in synthetic biology research and cellular immunotherapy development as a critical tool for standardized cell processing and manufacturing of clinical-grade cell products.
Item Stats
Product details
| Pump Speed | 2-400 ml/min |
| Atmosphere control | Gas mix unit for CO2, compressed air, and N2; min. pressure: 1 bar, max. pressure: 2.5 bar |
| Temperature Control | 4°C to 38°C |
| Centrifugation | Up to 2500 rpm (400 x g) |
| Microscope Camera | Up to 400x |
| Display/Controls | Full color, 10.1” TFT touchscreen |
| MACS tube sealer | For sealing CliniMACS Prodigy Tubing Sets PVC Tubes |
| Types of starting material | Leukapheresis, bone marrow, cryopreserved PSCs |
| Available cell processing steps | Cell washing, density gradient centrifugation, cell activation, fluorescent antibody labeling of cells, cell depletion and / or enrichment via magnetic cell separation, viral transduction, cell expansion, expansion and differentiation of adherent cells, cell culture and medium exchange, formulation of final cell product |
| IPC/QC | Integrated IPC/QC sampling pouches allow sterile sample removal |
| Manufactured in | Germany |
| Dimensions | 29x16x19” |
| Weight | 155 lbs |
| Electrical | 100-240V, 50/60Hz, 810VA |
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