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Agilent 6230B Accurate-Mass Orthogonal-Acceleration TOF Mass Spectrometer

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Product Description

The Agilent 6230B Accurate-Mass TOF Mass Spectrometer is a high-performance time-of-flight (TOF) MS designed for precise, high-resolution mass measurements in applications such as drug discovery, metabolomics, and environmental analysis.

  • Mass Range: m/z 25 to 20,000
  • Mass Accuracy: < 1 ppm at m/z 609.2807
  • Spectral Acquisition Rate: 30 spectra/second (m/z 100 to 3,200)
  • Resolving Power: 22,000 FWHM
  • Dynamic Range: Spans five orders of magnitude for trace-level detection

Key Technical Features:

  • Orthogonal acceleration TOF design reduces entrance velocity effects, enhancing resolution.
  • Agilent Jet Stream (AJS) electrospray ionization (ESI) technology improves ionization efficiency and sensitivity, enabling low picogram detection limits.
  • Automated tuning and calibration minimize user intervention and maintain optimal ion optics and mass axis alignment.
  • Real-time internal reference mass correction via built-in calibrant delivery ensures mass accuracy stability.
  • Fast polarity switching (<1 second) allows versatile positive/negative ion analysis.
  • Single-point data control integrates seamless coordination with HPLC systems, including automated error and leak management.
  • Optional in-source dissociation for enhanced fragmentation and untargeted screening capabilities.

Additional Capabilities:

  • Supports multiple ionization sources: ESI, APCI, APPI, multimode (ESI/APCI), HPLC-Chip/MS interface, and AP/MALDI PDF+ sources.
  • MassHunter software suite offers advanced molecular profiling with Find by Formula for compound ID based on accurate mass, isotopic patterns, and chemical composition.
  • High throughput suitable for ultra-high performance liquid chromatography (UHPLC) separations.
  • Mass accuracy stability of 2 ppm under temperature fluctuations.

This recertified and factory-calibrated instrument is delivered complete with necessary installation and setup equipment, fully tested to factory specifications.


Item Stats

Status
For Sale
State
used
Location
Hampton - United States
Shipping Info
2 to 3 Weeks

Product details

MS Sensitivity with AJS (Included)Signal-to-noise ratio > 50:1, Noise = 1 × RMS (1 pg reserpine injected on-column, measured at m/z 609.2807)
MS Sensitivity with ESI (Option 200)Signal-to-noise ratio > 10:1, Noise = 1 × RMS (1 pg reserpine injected on-column, measured at m/z 609.2807)
Mass Resolving Power22,000 FWHM (measured at m/z 1,522 after automatic tuning procedure)
Mass Accuracy - MS Mode< 1 ppm (measured at m/z 609.2807 using an internal reference mass)
Spectral Acquisition Rate - MS Mode30 spectra/second (spectra acquisition from m/z 100 to 3,200)
Dynamic RangeUp to 5 decades (in-scan dynamic range on co-eluting components)
Mass Rangem/z 25 to 20,000
Polarity Switching< 1 sec (pos/neg switching)
Mass Accuracy Temperature Stability - MS ModeMaintain 2 ppm mass accuracy within 2°C drift per hour (temperature: 15°C to 35°C (59°F to 95°F) at constant temperature while setting autotune at 25°C)
Single Point of ControlSingle point data system method capability with full control for HPLC system and TOF, stopping sample injection if errors or leaks occur
Ionization sourcesElectrospray (ESI), Atmospheric pressure chemical ionization (APCI), Atmospheric pressure photoionization (APPI), Multimode source (ESI and APCI), HPLC-Chip/MS interface, AP/MALDI PDF+ source
Transparent Introduction of Reference MassesDual-sprayer orthogonal ESI source, built-in calibrant delivery system, real-time internal reference mass correction for MS operation and heated sources
AutotuneAutomated optimization of ion optics and full TOF MS mass axis calibration
Data Mining ToolsOne-button extraction of compound-specific spectral and chromatographic information using find compounds algorithms
Molecular Profiling ToolsMeasurement of molecular features from LC/MS analyses (MassHunter), differential expression analysis with optional MassHunter Mass Profiler
Sound Emission< 70 db
Dimensions (L x W x H)32.7 x 28.7 x 52.4 in. (83 x 73 x 133 cm)
Weight260 lb. (117.9 kg)
Electrical Requirements200-220VAC, 50/60Hz, 15A

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From €59,259.14*ex. VAT

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