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Agilent 6130B Single Quadrupole Mass Spectrometer with 1260 Infinity I LC System
Product Description
The Agilent 6130B Single Quadrupole Mass Spectrometer integrated with the 1260 Infinity I LC System offers:
- Mass range: 10 to 3,000 m/z
- Mass accuracy: ±0.13 Da
- Scan speed: 10,400 Da/sec
- Ultrafast ion polarity switching: 30 msec for efficient data collection
- Ionization sources supported: ESI, APCI, APPI, multimode options
- Dynamic range: Greater than 6 × 10⁶ for quantitation reliability
- Mass drift stability: Less than 0.1 amu drift over 12 hours
- Detector: High-performance electron multiplier horn with high gain
- Software: Fully controlled by Agilent ChemStation Workstation Software
- SIM sensitivity: Signal-to-noise ratio above 250:1 (ESI positive mode)
- SIM dwell time: Maximum 5 msec for fast quantitation
- Vacuum system: Turbo-molecular and mechanical pump combination
This system enables: rapid compound screening, molecular weight confirmation, purification of targets from complex mixtures, accurate quantitation, and impurity identification. The ultrafast scan speed complements UHPLC separations and narrow LC peaks.
The turnkey system includes:
- Agilent 6130B Single Quad Mass Spectrometer
- 1260 Infinity I LC System components including:
- G4212B Diode Array Detector (tests: filter, dark current, Holmium oxide spectrum, lamp intensity, wavelength accuracy, baseline noise)
- G1312B Binary Pump (pressure up to 400 bar, leak test)
- G1316A Column Compartment (thermostat test for Peltier cooling/heating)
- G1329B Autosampler (injector step functionality test)
- Full system 4 Peak Test confirming HPLC functionality
All components are factory calibrated, recertified, and tested to meet original specifications, ready for immediate installation and operation.
Item Stats
Product details
| Maximum Scan Speed | 10,400 Da/sec |
| SIM Sensitivity, ESI Positive | Signal-to-noise ratio > 250:1 (1 pg of reserpine injected on column, quantifying the m/z 609 ion) |
| SIM Sensitivity, APCI Positive | Signal-to-noise ratio > 100:1 (1 pg of reserpine injected on column, quantifying the m/z 609 ion) |
| Polarity Switching | 30 msec (switching time from positive to negative polarity) |
| Mass Resolution (Autotune) | Unit resolution (full width at half maximum) |
| Mass Stability | < 0.1 amu or 100 ppm, whichever is larger (over 12 hours) |
| Mass Accuracy | ± 0.13 Da |
| Maximum SIM Dwell Time | 5 msec |
| Maximum SIM Transitions | 100 (one time segment) |
| Dynamic Range | > 6 × 10 6 |
| Mass Range | 10–3,000 m/z |
| Single Point of Control | Single-point data system method capability with full control of Agilent 1200 Series LC Systems and 6100 Series Single Quadrupole LC/MS Systems |
| Time Programming | SIM ion selections, Scan functions, Fragmentor voltage, External CAN valves |
| Ionization Sources | Electrospray (ESI), Multimode source (simultaneous ESI and APCI), Atmospheric pressure chemical ionization (APCI), ChipCube for intergrated nanoLC, Atmospheric pressure photoionization (APPI) |
| Detector | High energy conversion dynode and high gain electron multiplier horn |
| Vacuum System | One turbo-molecular pump with one mechanical pump |
| Dimensions (W x H x D) | 14 x 18 x 25 in. (35 x 45 x 63.5 cm) |
| Weight | 137.6 lb. (63.4 kg.) |
| Electrical Requirements | 200-230VAC, 60Hz or 200-240VAC, 50Hz |
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