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Pall Biotech UF/DF Tangential Flow Filtration System for Biopharmaceutical Processing
Product Description
The Pall Biotech UF/DF Tangential Flow Filtration System is a stainless steel skid designed for ultrafiltration and diafiltration (UF/DF) processes integral to biopharmaceutical manufacturing and biotechnology workflows. Engineered and manufactured in Germany, this GMP-ready TFF system supports pilot and GMP downstream processing by concentrating and exchanging buffers for biologics such as monoclonal antibodies, recombinant proteins, enzymes, viral vectors, and gene therapy products.
Key features include:
- 316L stainless steel construction optimized for hygiene and cleanroom compatibility
- Integrated touchscreen Human-Machine Interface (HMI) with intelligent PLC enables precise control of pressure, flow, and temperature
- Maximum operating pressure of 4 bar (58 psi) and temperature range from 5°C to 80°C
- Compact skid design with lockable castors for enhanced mobility within classified environments
- System supports both single-use and reusable membrane compatibility, facilitating flexibility in biotechnology and molecular diagnostics workflows
- Validated safety measures with emergency stop, pressure alarms, and lockable panels ensure compliance with regulated bioprocess production
This system is ideal for applications including:
- Concentration and buffer exchange in biopharmaceutical drug substance manufacturing
- Purification steps in monoclonal antibody production
- Processing of gene therapy components such as viral vectors, plasmid DNA, and mRNA
- Enzyme and protein product downstream processing
- Clarification of cell culture lysates and spent media
- Final formulation and buffer exchange prior to sterile filtration and fill/finish stages
Designed to optimize process efficiency and maintain product recovery, the Pall UF/DF system minimizes hold-up volume and protects membrane integrity, making it critical in bioprocessing pipelines, molecular cloning workflows, and synthetic biology research. Its scalability and validated platform position it as a reliable technology for both research and production environments targeting biopharmaceutical and gene therapy development.
Item Stats
Product details
| Manufacturer | Pall |
| Model | UF/DF |
| Year | 2022 |
| Condition | Used |
| Serial Number | 05000943 |
| Stock Number | 55165 |
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