GE Healthcare Uniflux 10 TFF System

The GE Healthcare Uniflux 10 TFF System is in optimal working condition, ready for immediate deployment. It comes equipped with two Watson Marlow 520BP Pumps. This system is part of a dedicated series designed specifically for tangential flow filtration (TFF), supporting processes from pilot studies to full-scale manufacturing. The Uniflux 10 ensures complete automation, enhancing productivity by providing consistent, repeatable, and validatable filtration results.

The system accommodates an adjustable flow rate from 0.5 to 10 liters per minute, allowing the versatile handling of different sample volumes to meet varied process requirements. It includes options for both recirculatory and single-use mixing systems, simplifying both setup and maintenance.

Key features of the UniFlux 10 include the integration of UNICORN Control Software, facilitating automated operations with comprehensive data logging in compliance with FDA regulations, especially suitable for 21 CFR Part 11 applications. Operators familiar with GE Healthcare’s chromatography solutions will appreciate the user-friendly interface, akin to the well-known ÄKTA series. The system is capable of microfiltration (MF) and ultrafiltration (UF), utilizing high-performance cross flow filters.

The diaphragm pump technology ensures a stable flow rate, while the optional triple inlet valve allows for the smooth introduction of multiple liquids, optimizing efficiency without requiring tubing changes.

Applications include biopharmaceutical production for monoclonal antibodies and vaccines, cell culture processing to recover valuable biomolecules, and buffer exchange and diafiltration for downstream processing preparations.