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Eppendorf BioFlo 320 DUAL Bioprocess Control System for Glass Autoclavable & Single-Use Bioreactors

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Product Description

The Eppendorf BioFlo 320 DUAL Bioprocess Control System is a versatile and compact benchtop controller tailored for advanced upstream bioprocessing applications in biotechnology, molecular diagnostics, and biopharmaceutical production. Compatible with glass autoclavable jacketed vessels (1.0L to 10L) and Eppendorf BioBLU single-use bioreactors, it supports cell culture and microbial fermentation workflows with precision. This system is widely adopted in synthetic biology research and critical in biomanufacturing pipelines.

Key Technical Features:

  • Dual-controller setup: Includes two BioFlo 320 units allowing parallel bioprocess control.
  • Vessel compatibility: Supports glass/autoclavable vessels (1–10 L) and BioBLU single-use vessels (ranging from 0.3 L to 50 L), adaptable for microbial or mammalian cell culture.
  • Gas flow management: Integrated Thermal Mass Flow Controllers (TMFC) for 4 gases (Air, N₂, O₂, CO₂) with gas-in supply ports up to 10 psig (glass vessels) and 6 psig (single-use vessels). Optional sparge and overlay gas flow control with flow ranges from 0.002 to 20 SLPM.
  • Sensors and digital inputs: Accepts PT100 temperature probes, pH, dissolved oxygen (DO), Redox, and CO₂ sensors with capacity for up to two additional digital sensors. Optional optical pH sensor connector available.
  • Agitation and pumping: Two vessel drive options available (direct or magnetic). Integrated four peristaltic pumps with variable speed control (Watson-Marlow heads), supporting precise media feeding for bioprocess optimization. External pumps can be added.
  • Temperature control: Supports heated blankets for single-use vessels and liquid-cooled exhaust condensers with operating temperature ranges tailored for vessel types.
  • Data and control interface: ELO touchscreen monitor with responsive interface for real-time process monitoring and parameter adjustments.
  • Physical specifications: Compact dimensions (40.6 x 40.6 x 66.0 cm), 32 kg weight, and flexible power input (100-120/208-240 VAC).

Bioprocessing Applications:

  • Upstream process development in molecular cloning and synthetic biology.
  • Microbial fermentation optimization for bioprocess scale-up/down studies.
  • Mammalian/hybridoma cell culture for biotechnology and clinical diagnostics.
  • Critical control in biopharmaceutical manufacturing pipelines including gene editing workflows.
  • Live-cell culture monitoring integrating pH, DO, and gas control sensors for enhanced bioprocess reproducibility.

System Customization and Options:

  • Vessel volumes and impeller types (pitched blade, marine, Rushton) adaptable per research requirements.
  • Optional external chiller systems, cooling loops, and Peltier condensers for precise temperature regulation.
  • Extended gas regulation kits, vessel scales, foam/level sensors, and vessel baffling available for enhanced process control accuracy.

Included with Purchase:

  • Two BioFlo 320 bioprocess control stations.
  • ELO touchscreen monitor with arm mount.
  • Corresponding bioreactor drive agitation motors matched to vessel size.
  • Four-gas regulator with valves.
  • Calibrated pH and DO sensors with cables.
  • Bench scales and additional accessories for complete operation.

This system is widely used in biotechnology laboratories for essential upstream bioprocessing tasks, from bench-scale microbial fermentations to mammalian cell culture processes, optimizing parameter control in molecular diagnostics and synthetic biology workflows. The BioFlo 320 DUAL system supports scalable bioprocessing and is critical in biopharmaceutical production pipelines.

Note: Glass vessels sold separately. Heated blankets provided free with BioBLU single-use vessel setups. Reliable warranty, remote setup, and operational training ensure smooth integration into laboratory environments focused on bioprocess engineering and cell imaging applications.


Item Stats

Status
For Sale
State
used
Model
BioFlo 320 DUAL
Location
Walpole - United States

Product details

StockIn Stock
BrandEppendorf
Product CodeSM101332-2ACV
ConditionPre-Owned

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