Bruker Berkeley Lights Beacon CAS 2.4 Premium Optofluidic Single-Cell Analysis System with Fluidics Station

The Bruker Berkeley Lights Beacon CAS 2.4 Premium is a cutting-edge optofluidic single-cell analysis system designed for precise manipulation and characterization of individual cells in biotechnology research and development. This integrated platform combines advanced microfluidic chip arrays and fluorescence imaging to enable non-contact, light-driven positioning of cells within nanoliter-scale NanoPen chambers (500 pL or 1 nL). The system supports high-throughput single-cell screening, essential for applications such as monoclonal antibody discovery, cell line development, T-cell and immune profiling, and functional genomics.

Key technical features include:

This system is widely adopted in biotechnology and molecular diagnostics workflows, supporting gene editing research, bioprocessing, and biopharmaceutical production pipelines. The fluidics station uses multi-channel syringe pumps to streamline media and reagent flow, critical for maintaining physiological conditions during single-cell assays. Its modular design and automated handling are critical for synthetic biology research and cell therapy development.

Dimensions of the fully integrated unit are approximately 46 in (W) × 34 in (D) × 71.5 in (H), with a weight around 1,260 lbs. The system operates on 110–240 V AC with 50–60 Hz frequency. Although sold as-is without consumables, this instrument provides a robust platform for labs focused on personalized medicine, antibody discovery, and advanced cell profiling.

This Beacon system is essential for single-cell phenotypic screening, enabling biologists and clinical researchers to conduct comprehensive, automated experiments that were previously unattainable at high throughput. It supports seamless integration into biomanufacturing workflows and is a cornerstone technology for workflows in synthetic biology and molecular cloning applications.

Primary Keywords included: optofluidic single-cell analysis system, fluorescence imaging, automated single-cell manipulation, microfluidic cell handling
Long-tail Keywords included: light-driven cell positioning within nanoliter scale chambers, high-throughput single-cell screening for antibody discovery, automated workflows for biopharmaceutical production pipelines, critical system for cell line development and functional genomics, essential for molecular diagnostics and cell therapy research