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Bruker Berkeley Lights Beacon CAS 2.4 Premium Single-Cell Optofluidic Analysis System
Product Description
The Bruker Berkeley Lights Beacon CAS 2.4 Premium is an advanced single-cell analysis system integrating optofluidic technology for precise manipulation, imaging, and functional profiling of individual cells. This platform combines semiconductor optics, nanofluidics, and real-time optical monitoring to support biotechnology workflows such as molecular diagnostics, gene editing applications, and bioprocessing research.
Key Technical Features:
- Optofluidic single-cell manipulation: Uses OptoSelect chips with light-driven positioning of cells into NanoPen chambers (500 pL or 1 nL volumes) for isolation and analysis.
- Fluorescence imaging module: Equipped with Nikon Plan Fluor 10x/0.30 DIC-capable and 4x/0.28 objectives, paired with a high-sensitivity Andor Zyla sCMOS camera, enabling detailed fluorescence and brightfield imaging.
- Multi-channel microfluidic control: Integrated fluidics system with reagent reservoirs, automated reagent handling, and a chip docking fluidic interface for complex assay workflows.
- DLP-based optoelectronic positioning (OEP): Uses patterned light via a DLP projector to precisely manipulate single cells and conduct sequential or simultaneous multi-assay workflows.
- Environmental gas control: Ibidi CO₂/O₂ gas mixer controller supports live-cell culture conditions with temperature control from 10°C to 40°C and gas supply >99% CO₂, essential for live-cell assays in synthetic biology and biopharmaceutical pipelines.
- Software Suite: Runs Cell Analysis Suite (CAS) v2.4 Premium and Assay Analyzer 2.4 for assay design, analysis, and live-cell export for downstream genomic or proteomic workflows.
Applications in Research and Biotechnology:
- Single-cell antibody discovery and screening critical for therapeutic biomanufacturing
- Cell line development, clone selection, and phenotype-to-genotype correlation essential for molecular cloning workflows
- Functional immune cell profiling and single-cell secretion assays widely adopted in synthetic biology and molecular diagnostics
- Live-cell export capability supporting integrative downstream analysis in biomedical engineering and clinical diagnostics
Physical and Operational Specifications:
- Dimensions: 46 in (W) × 34 in (D) × 71.5 in (H)
- Weight: Approximately 1,260 lb
- Power: 110–240 V AC, 50–60 Hz
- Gas requirements: Compressed dry air (CDA) and high-purity CO₂ (>99%) supply
This system's automated optofluidic technology and integrated fluorescence imaging make it a critical instrument for laboratories engaged in advanced single-cell studies, offering precise cell manipulation and essential environmental controls to maintain live-cell conditions. It is ideal for researchers in biotechnology, molecular biology, and clinical diagnostics looking to enhance throughput and data quality in cell-based assays.
Primary keywords used: single-cell analysis system, optofluidic system, fluorescence imaging, microfluidic control
Long-tail keywords incorporated: automated single-cell manipulation platform, optoelectronic positioning for cell assays, environmental gas control for live-cell imaging, essential for molecular cloning workflows, widely adopted in synthetic biology research, critical in biopharmaceutical production pipelines.
Item Stats
Product details
| Stock | In Stock |
| Brand | Bruker Berkeley Lights |
| Product Code | 63013 |
| Condition | Pre-Owned |
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