Offering the best quotes for your research!
New and used scientific instruments
🚚 Shipping Worldwide 🌎
✉️ info@questpair.com
Unchained Labs Uncle Protein Stability Analyzer Unit 2 with Fluorescence, SLS, and DLS Technologies
Product Description
The Unchained Labs Uncle Protein Stability Analyzer Unit 2 is a compact, high-throughput biophysical characterization system designed for comprehensive protein stability and aggregation analysis, widely used in biotechnology, molecular diagnostics, and biopharmaceutical research.
- Multimodal analysis techniques: full-spectrum fluorescence, static light scattering (SLS), and dynamic light scattering (DLS) enable simultaneous measurement of melting temperature (Tm), aggregation temperature (Tagg), particle sizing, and polydispersity.
- Sample handling: minimal sample volume requirement of 9 μL in sealed capillaries facilitates analysis of limited or precious biologics, supporting up to 48 samples per run for efficient screening workflows.
- Temperature control: precise regulation from 15 to 95 °C with ±0.1 °C accuracy and adjustable heating rates (0.1–10 °C/min) supports thermal stability and isothermal studies critical in protein characterization and formulation development.
- Fluorescence detection: excitation at 266 nm and 473 nm lasers with CCD spectrometer covering 250–720 nm spectral range enables sensitive detection of unfolding events and conformational changes in proteins and biologics.
- Light scattering capabilities:
- SLS detects molecular mass changes down to ~15 kDa and quantifies aggregation relevant for bioprocessing and gene editing vector evaluation (e.g., AAV capsid concentration ≥5 x 10¹¹ viral genomes/mL).
- DLS measures hydrodynamic diameter from 0.3 to 1000 nm with ±2% size accuracy, essential for nanoparticle sizing, formulation stability, and viscosity analysis in synthetic biology and biomanufacturing contexts.
- Applications: thermal shift assays (Tm, Tagg), isothermal stability profiles, viscosity/interaction parameter measurements (kD, B22, G22, ΔG), particle sizing with thermal ramp, and recovery studies, supporting molecular cloning workflows and bioprocess development.
- Operational features: fast analysis enabled by intuitive software, combined with fully integrated fluorescence and scattering technologies, streamline protein stability screening, aggregation detection, and biophysical profiling in biotechnology and clinical diagnostics laboratories.
This instrument is essential for laboratories involved in protein engineering, therapeutic antibody development, and biopharmaceutical production pipelines requiring reliable, low-volume, high-throughput protein stability and aggregation characterization.
Item Stats
Product details
| Stock | In Stock |
| Brand | Unchained Labs |
| Product Code | SM101017-U2 |
| Condition | Pre-Owned |
About QuestPair
Our Mission
QuestPair is Europe's leading platform for scientific equipment, connecting researchers and organizations with verified suppliers of both new and pre-owned laboratory instruments in the biotech and material science industry. Our aim is to make the procurement of scientific instruments more efficient, cost-effective, and reliable, so that laboratories can focus on advancing science rather than searching equipment and negotiating deals.
Why Choose Us
Founded by scientists for scientists, we understand your challenges. Our AI-powered platform offers transparent pricing, verified quality, and expert support, ensuring you find the perfect equipment for your research needs.
Verified Quality
Every piece of equipment undergoes thorough verification by our expert team, ensuring reliability and performance.
Cost Efficiency
Access both new and premium pre-owned equipment, saving up to 40% without compromising on quality.
Expert Support
Our dedicated team provides personalized guidance throughout your equipment procurement journey.
Ready to Transform Your Research?
Join thousands of biotech scientists who trust QuestPair for their equipment needs.
What customers think about QuestPair
Brilliant service. Everything arrived and was exactly as expected
Jon Welburn
Great customer service! Got me great options for the equipment I was looking for and in a timely manner.
Pamela
Space Lab Technologies, LLCHarm is very responsive to help me find the right equipment. The product I received is in a good condition.
Ph.D. Hsin-Wen Liang
Northeastern UniversityPrice on Request
In Stock
Get a quote within one business day
Verified equipment
Trusted warranties & returns
Safe payment and fast delivery
Didn't find what you're looking for?
Our sales team specializes in sourcing custom and hard-to-find products to meet your exact specifications. Submit a request for a tailored quote.
Frequently Asked Questions
Is this equipment new or refurbished?
How long does shipping take?
What about warranty and returns?
Why request a quote?
Need help choosing the right tool?
- Accurate policy information specific to your chosen product
- Clear understanding of warranty coverage and terms
- Detailed return policy explanation
- Transparent shipping options and costs
Customer Service
Here to help you with: Product Inquiries, Shipping & Support, Technical Support, Business Inquiries and Press.
We are available to assist you Mon-Fri, 10am - 5pm CET.