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Malvern Creoptix WAVEdelta Label-Free Biosensor with WAVEsampler Autosampler
Product Description
The Malvern Creoptix WAVEdelta system is an advanced label-free biosensor platform employing Grating Coupled Interferometry (GCI) technology for precise real-time measurement of biomolecular interactions. Designed for applications in biotechnology, molecular diagnostics, and biopharmaceutical research, this benchtop instrument delivers highly sensitive kinetic and affinity analyses critical in protein–protein interaction kinetics, small molecule screening, and membrane protein studies.
Key technical specifications include:
- Noise (RMS): <0.01 pg/mm² at 1 Hz, ensuring low baseline noise for accurate detection of weak interactions.
- Drift: <0.3 pg/mm²/min, supporting stable long-duration measurements.
- Readout Frequency: Selectable at 1 Hz, 10 Hz, or 40 Hz for flexible data acquisition.
- Association Rate Constants: Ka range from 10² to 5×10⁷ M⁻¹s⁻¹ (small molecules) and up to 3×10⁹ M⁻¹s⁻¹ (large molecules).
- Dissociation Rate Constants: Kd from 10⁻⁶ to 10 s⁻¹, capturing a broad spectrum of binding kinetics.
- Temperature Control: Analysis range from 4°C to 45°C with capacity to maintain 15°C below ambient temperature.
- Flow System: Four parallel fluidic channels with sealed disposable flow cells integrated into WAVEchips (consumables sold separately).
- Flow Rate: Adjustable flow between 1 and 400 μL/min compatible with crude biological samples.
The included WAVEsampler Autosampler supports automated sample handling with:
- Two 48-vial racks (1.5 mL positions)
- Four-buffer automatic switching
- Injection volumes less than 450 μL (100 μL typical)
- Sample storage at ambient or refrigerated conditions (4°C–20°C)
- Sample recovery capabilities to minimize waste
Data processing features incorporate:
- Automated kinetic and affinity calculations (ka, kd, KD)
- Predefined kinetic modeling and evaluation workflows
- Supports direct kinetics, CFCA (calibration-free concentration analysis), ligand screening, and waveRAPID protocols
The system’s robust fluidics and compact benchtop design offer low maintenance and high reliability, making it well-suited for demanding bioprocessing, gene editing, and synthetic biology research workflows. It is widely adopted in biopharmaceutical production pipelines for antibody characterization, epitope binning, and lead optimization.
This pre-owned unit is fully serviced and tested to meet stringent operational standards, includes a PC with Creoptix WAVEcontrol software (V4.9.3), tubing, power and communications cables, and two 48-vial racks. Consumable WAVEchips are required separately.
Ideal for researchers and lab managers seeking a cost-effective, high-performance biosensor platform optimized for molecular cloning workflows, cell surface interaction analysis, and biomedical engineering applications.
Primary Keywords: label-free biosensor, Grating Coupled Interferometry, kinetic affinity analysis, molecular interaction analyzer
Long-Tail Phrases: high-sensitivity binding analysis with GCI technology, automated autosampler for sample throughput, widely used in biopharmaceutical production pipelines, essential for molecular cloning workflows, robust fluidics system for biomolecular interaction studies
Item Stats
Product details
| Stock | In Stock |
| Brand | Malvern |
| Product Code | 61172 |
| Condition | Pre-Owned |
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