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Agilent 6230A Accurate-Mass Orthogonal Acceleration TOF Mass Spectrometer with 1200 LC System


Product Description

The Agilent 6230A is a high-performance orthogonal acceleration time-of-flight (oa-TOF) mass spectrometer coupled with the Agilent 1200 LC system for advanced analytical applications. Key features include:

  • Mass Range: m/z 25 to 20,000
  • Mass Accuracy: < 1 ppm at m/z 609.2807
  • Resolving Power: 22,000 FWHM
  • Spectral Acquisition Rate: Up to 30 spectra/sec (m/z 100–3,200)
  • Ionization Technology: Agilent Jet Stream Electrospray Ionization (AJS ESI) for high sensitivity and low pg detection limits
  • Dynamic Range: Five orders of magnitude to detect trace-level compounds in complex matrices
  • Dual-Sprayer Orthogonal ESI Source: Enables real-time internal reference mass correction with an integrated calibrant delivery system
  • Polarity Switching: < 1 second for positive/negative ion analysis adaptability
  • Automated Tuning and Calibration: Optimizes ion optics and mass axis alignment with minimal user intervention
  • In-Source Dissociation (optional): For untargeted screening and enhanced fragmentation data
  • Integration: Single-point control seamlessly manages HPLC and MS workflows, including error handling to stop sample injections on leak or error detection
  • Supported Ion Sources: ESI, APCI, APPI, multimode (ESI and APCI), HPLC-Chip/MS, AP/MALDI PDF+
  • Applications: Drug discovery, metabolomics, environmental analysis, biologics characterization (monoclonal antibodies, glycoforms)
  • 1200 LC System Diagnostics:
    • G1315C Diode Array Detector (filter, dark current, lamp intensity, wavelength accuracy, baseline noise tests)
    • G1312B Binary Pump (pressure up to 400 bar, leak tests)
    • G1316A Column Compartment (thermostat cooling/heating evaluation)
    • G1329A Autosampler (injector movement/functional testing)
    • System-wide 4 Peak Isocratic Standard Test

This system has been factory recertified and calibrated, ready for immediate deployment. It comes complete with installation and setup materials, and all components are verified to meet factory performance specifications. The MassHunter software suite supports advanced data analysis, including formula finding based on accurate mass and isotopic patterns, enabling confident compound identification and elemental formula determination.


Item Stats

Status
For Sale
State
used
Brand
Agilent
Model
6230A Accurate-Mass TOF Mass Spectrometer with 1200 LC System
Location
Hampton - United States
Shipping Info
2 to 3 Weeks

Product details

MS Sensitivity with AJS (Included)Signal-to-noise ratio > 50:1, Noise = 1 × RMS (1 pg reserpine injected on-column, measured at m/z 609.2807)
MS Sensitivity with ESI (Option 200)Signal-to-noise ratio > 10:1, Noise = 1 × RMS (1 pg reserpine injected on-column, measured at m/z 609.2807)
Mass Resolving Power22,000 FWHM (measured at m/z 1,522 after automatic tuning procedure)
Mass Accuracy - MS Mode< 1 ppm (measured at m/z 609.2807 using an internal reference mass)
Spectral Acquisition Rate - MS Mode30 spectra/second (spectra acquisition from m/z 100 to 3,200)
Dynamic RangeUp to 5 decades (in-scan dynamic range on co-eluting components)
Mass Rangem/z 25 to 20,000
Polarity Switching< 1 sec (pos/neg switching)
Mass Accuracy Temperature Stability - MS ModeMaintain 2 ppm mass accuracy within 2°C drift per hour (temperature: 15°C to 35°C (59°F to 95°F) at constant temperature while setting autotune at 25°C)
Single Point of ControlSingle point data system method capability with full control for HPLC system and TOF, stopping sample injection if errors or leaks occur
Ionization sourcesElectrospray (ESI), Atmospheric pressure chemical ionization (APCI), Atmospheric pressure photoionization (APPI), Multimode source (ESI and APCI), HPLC-Chip/MS interface, AP/MALDI PDF+ source
Transparent Introduction of Reference MassesDual-sprayer orthogonal ESI source, built-in calibrant delivery system, real-time internal reference mass correction for MS operation and heated sources
AutotuneAutomated optimization of ion optics and full TOF MS mass axis calibration
Data Mining ToolsOne-button extraction of compound-specific spectral and chromatographic information using find compounds algorithms
Molecular Profiling ToolsMeasurement of molecular features from LC/MS analyses (MassHunter), differential expression analysis with optional MassHunter Mass Profiler
Sound Emission< 70 db
Dimensions (L x W x H)32.7 x 28.7 x 52.4 in. (83 x 73 x 133 cm)
Weight260 lb. (117.9 kg)
Electrical Requirements200-220VAC, 50/60Hz, 15A

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