Agilent G1946B Benchtop Quadrupole LC/MS Detector with ESI and APCI Ionization

The Agilent G1946B is a benchtop quadrupole liquid chromatography/mass spectrometry (LC/MS) detector designed for seamless integration with Agilent 1100 series HPLC systems. This advanced mass spectrometer offers a broad mass range of 2 to 3000 m/z with high accuracy of ±0.13 u in calibrated scan mode, enabling precise identification and characterization of large biomolecules, including modified proteins essential in biotechnology applications such as molecular diagnostics and bioprocessing.

Key technical features include:

This LC/MS detector is essential for applications demanding high sensitivity and specificity in compound identification, chromatographic peak purity verification, and quantitative trace analysis. Though currently sold AS-IS for parts, the internal components may be valuable for repair or research use. The system does not include computer or software and is manufactured in the United States.

This instrument supports molecular biology workflows by enabling critical mass spectrometric analysis used in gene editing research, protein characterization, and other biotechnology research fields. Its advanced API sources make it a key tool widely adopted in biopharmaceutical production pipelines and molecular cloning workflows requiring detailed mass spectrometric data.

Keywords: benchtop quadrupole LC/MS, mass spectrometer, electrospray ionization, atmospheric pressure chemical ionization, biomolecule analysis, biotechnology research, molecular diagnostics, bioprocessing, synthetic biology applications, trace quantitation, compound identification