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Axon Axopatch 200B Patch Clamp Amplifier with CV 203BU Headstage, Digidata 1550B Digitizer, and pCLAMP 11 Software
Product Description
The Axon Axopatch 200B is a precision patch clamp amplifier optimized for electrophysiology applications in neuroscience, cardiac physiology, and biomedical engineering. This system includes the CV 203BU single-channel headstage, the Axon Digidata 1550B low-noise digitizer, and the pCLAMP 11 software suite on a dedicated data acquisition PC, delivering a complete solution for advanced ion channel and membrane biophysics research.
Key technical features include:
- Dual-mode operation for voltage clamp and current clamp measurements with ultra-low-noise capacitive feedback technology enabling stable gigaseal recordings.
- Fast compensation for capacitive and series resistance artifacts improves signal fidelity during single-channel, whole-cell, and excised patch experiments.
- Integrated low-pass Bessel filter with selectable cutoff frequencies aids in noise reduction during signal acquisition.
- Scaled analog outputs (I_Mon, V_Mon, Command) facilitate real-time electrophysiological monitoring.
- Compatible with low-capacitance pipette holders and Ag/AgCl electrodes, essential for molecular diagnostics and electrophysiology workflows.
The Digidata 1550B digitizer enhances data quality, offering:
- Up to 500 kHz sampling rate per channel with 16-bit A/D and D/A resolution for capturing rapid biological events and high-frequency stimuli.
- 8 analog input channels, 4 analog output channels, and 16 digital I/O lines (8 input / 8 output) allow for complex multi-phase protocols and synchronization with optical imaging or stimulation systems.
- Engineered low-noise design with separate A/D and D/A converters and enhanced shielding reduces digitizer-induced artifacts, critical in biopharmaceutical and synthetic biology research settings.
- USB 2.0 high-speed interface for reliable, high-throughput data acquisition.
The included pCLAMP 11 software suite supports:
- Programmable voltage/current protocols, seal test, series resistance compensation, and leak subtraction for precise electrophysiological control.
- Stimulus waveform design, online and offline filtering, peak analysis, and event detection for detailed data interpretation.
- Integration with multi-modal experimental setups in live-cell imaging, optogenetics, gene editing, and neuroscience research.
This system is widely adopted in biotechnology laboratories requiring robust instrumentation for ion channel research, synaptic physiology, biomedical engineering, and clinical molecular diagnostics. The package includes comprehensive cables, power supplies, and a USB license dongle, backed by warranty and remote setup training options.
Applications:
- Whole-cell, single-channel, and excised patch clamp recordings.
- Synaptic current and action potential analysis.
- Drug response assays in neuropharmacology and cardiovascular research.
- Integration with optogenetic and fluorescence imaging platforms for combined electrophysiology and cell imaging studies.
Optional accessories include additional headstages, vibration isolation tables, perfusion systems, temperature controllers, and imaging hardware to tailor the system to specific experimental protocols.
This pre-owned unit has been thoroughly serviced and tested, ensuring operational reliability for demanding bioprocessing and molecular biology research workflows where signal integrity and data precision are paramount. The Axopatch 200B system with Digidata 1550B and pCLAMP 11 is an essential instrument for biopharmaceutical production pipelines requiring high-fidelity electrophysiological data acquisition and analysis.
Item Stats
Product details
| Stock | In Stock |
| Brand | Axon |
| Product Code | SM100021-1550B |
| Condition | Pre-Owned |
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