Axon Axopatch 200B Patch Clamp Amplifier System with Digidata 1440A Digitizer and pCLAMP 11 Software

The Axon Axopatch 200B system integrates a low-noise, high-precision patch clamp amplifier with a CV 203BU single-channel headstage, enabling advanced whole-cell, cell-attached, inside-out, and outside-out electrophysiological recordings. Designed for membrane biophysics and ion channel studies, this amplifier features high input impedance, low capacitance design, and built-in capacitive/resistive compensation circuitry, ensuring precise membrane potential recordings critical for neuroscience and molecular diagnostics.

Coupled with the Axon Digidata 1440A digitizer, this system supports USB 2.0 connectivity, delivering up to 250 kHz sampling rate per channel with 16-bit A/D conversion resolution. It includes 8 analog input channels, 4 analog output channels, and 8 digital I/O lines for high-fidelity voltage clamp and current clamp data acquisition. The integrated pCLAMP 11 software suite (including Clampex for data acquisition and Clampfit for analysis) provides real-time experimental control, automated pulse generation, seal testing, leak subtraction, and advanced event detection, essential for bioprocessing assays and synaptic physiology research.

This package includes a dedicated acquisition PC preconfigured for electrophysiology workflows with plug-and-play drivers, USB dongle license for pCLAMP software, and all necessary cables and connectors. The system supports remote instrument setup and training, ensuring streamlined integration into patch clamp rigs used in biomanufacturing and synthetic biology. Optional upgrades such as pipette holders, vibration isolation, Faraday cages, micromanipulators, and perfusion systems are also available for comprehensive electrophysiological experimentation.

Key Features:

This system is widely adopted in neuroscience, cell imaging, and synthetic biology research, offering robust performance for live-cell electrophysiology, membrane potential measurements, and biomedical engineering applications requiring accurate ion channel recordings. It is a critical instrument in molecular cloning workflows and biopharmaceutical production pipelines where precise electrophysiological characterization is required.