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Shimadzu Nexera Hybrid UHPLC System with Dual LC-20ADXR Pumps and SPD-40 UV-VIS Detector

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Product Description

The Shimadzu Nexera Hybrid UHPLC System features advanced components optimized for precise, high-throughput liquid chromatography essential in molecular diagnostics, biopharmaceutical production, and synthetic biology research. It integrates:

  • Dual LC-20ADXR Binary Gradient Pumps capable of flow rates from 0.0001 to 10 mL/min with ±0.06% RSD precision and maximum pressures up to 66 MPa, enabling robust gradient mixing critical for high-pressure UHPLC separations.
  • SPD-40 UV-VIS Detector with a deuterium lamp, 190–700 nm wavelength range, 10 mm optical path length, and low baseline noise/drift, facilitating sensitive absorbance detection in clinical and bioanalytical studies.
  • SIL-30ACMP Autosampler supporting up to 576 samples with precise sample injection (up to 50 µL), integrated rinse system, and compatibility with 96/384-well microtiter plates or vial racks—ideal for automated bioprocessing and high-throughput screening.
  • CTO-20A Column Oven employing forced air circulation for temperature stability within 4–85°C controlled to ±0.1°C, critical for reproducible chromatographic performance in biotechnological assays.
  • DGU-20A5R Degassing Unit with five flow lines and ~89% degassing efficiency at 1 mL/min, ensuring baseline stability by eliminating dissolved gases, essential for consistent UHPLC operation.
  • The system is controlled via the CBM-20A controller and operated through LabSolutions software, enabling real-time monitoring of flow rate, pressure, and gradient parameters, which is critical in biomanufacturing quality control pipelines.

This UHPLC system is widely adopted in pharmaceutical drug analysis, clinical diagnostics, environmental testing, food safety, and academic research. Its precision flow control, automated sample handling, and stable temperature regulation make it essential for workflows in molecular cloning, gene editing analytics, and synthetic biology applications.

Additional features include highly reliable leak sensors and low-use components ensuring longevity, and complete system integration with solvent trays and power conditioning. The instrument has been tested thoroughly, including flow rate accuracy, detector wavelength validation, autosampler injection repeatability, and temperature stability.

Ideal for:

  • Biotechnology laboratories requiring reproducible UHPLC separations
  • Molecular diagnostics workflows demanding precise UV absorbance detection
  • Biopharmaceutical QC with automated high-throughput sample injections
  • Synthetic biology research benefiting from binary gradient UHPLC control
  • Live-cell metabolites analysis and chemical purity profiling

Shimadzu’s Nexera Hybrid system offers a complete, ready-to-operate UHPLC solution combining precision engineering with high sensitivity and throughput, supporting rigorous analytical demands in biotechnology and biomedical engineering domains.


Item Stats

Status
For Sale
State
used
Model
Nexera Hybrid UHPLC System with Dual LC‑20ADXR Pumps, X2 SIL-30ACMP Autosampler, SPD‑40 UV-VIS Detector
Location
Walpole - United States
Category

Product details

StockIn Stock
BrandShimadzu
Product Code65407
ConditionPre-Owned

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