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Malvern Creoptix WAVEdelta GCI Label-Free Biomolecular Interaction Analysis System with WAVEsampler Autosampler
Product Description
The Malvern Creoptix WAVEdelta is a high-sensitivity Grating-Coupled Interferometry (GCI) biosensor system for real-time, label-free biomolecular interaction and binding analysis. The included WAVEsampler autosampler supports automated sample handling, improved throughput, and reproducible kinetic measurements.
The system is suited to protein–protein interaction studies, small-molecule and fragment screening, antibody characterization, epitope binning, membrane-protein analysis, and biopharmaceutical lead optimization. It can measure weak, transient, and high-affinity interactions without a lower molecular-weight limit.
Included configuration
- Malvern Creoptix WAVEdelta system
- WAVEsampler autosampler
- Two 48-vial racks with 1.5 mL positions
- PC with Creoptix WAVEcontrol V4.9.3
- Tubing and connections
- Power and communication cables
- WAVEchips are consumables and are not included
Performance specifications
- RMS noise: <0.01 pg/mm² at 1 Hz
- Drift: <0.3 pg/mm²/min
- Readout frequency: 1 Hz, 10 Hz, or 40 Hz
- Association constant range:
- Ka = 10²–5 × 10⁷ M⁻¹ s⁻¹ for small molecules
- Ka = 10²–3 × 10⁹ M⁻¹ s⁻¹ for large molecules
- Dissociation constant range: Kd = 10⁻⁶–10 s⁻¹
- Analysis temperature range: 4°C–45°C, maximum 15°C below ambient
- Molecular-weight limit: No lower limit
Fluidics and sample handling
- Four parallel flow channels
- Channel referencing: any combination of the four channels
- Sealed, disposable flow cells integrated into disposable WAVEchips
- Flow rate: 1–400 µL/min
- Compatible with crude samples
- Four-buffer automatic switching
- Injection volume: <450 µL, with 100 µL typical
- Sample storage: ambient or 4°C–20°C
- Sample recovery capability
Data analysis
- Kinetic affinity analysis: ka, kd, KD
- Automated data evaluation
- Predefined kinetic models
- Direct kinetics
- CFCA
- Ligand screening
- waveRAPID
The pre-owned WAVEdelta system was tested for power stability, initialization, PC communication, fluidic priming, chip detection, chip handling, DSMO test-sample operation, and system-test performance. It is appropriate for biotechnology, molecular interaction analysis, drug discovery, antibody development, and biopharmaceutical research workflows.
Item Stats
Product details
| Stock | In Stock |
| Brand | Malvern |
| Product Code | 61172 |
| Condition | Pre-Owned |
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