Agilent Advanced Analytical Oligo Pro II Automated Oligonucleotide Analyzer for High-Throughput UV Sizing

The Agilent Advanced Analytical Oligo Pro II is a benchtop automated oligonucleotide analyzer designed for high-throughput nucleic acid analysis, optimized for molecular diagnostics and biotechnology workflows. This system utilizes UV absorption spectroscopy at a fixed wavelength of 254 nm for dye-free detection, enabling direct quantification and sizing of oligonucleotides up to 60-mers without fluorescent labeling.

Key features include:

The system package includes a Dell laptop loaded with Oligo Pro II Controller Software v2.1.0.2 and Data Analysis Software v2.0.0.3, holders for skirted PCR microplates and deep-well microplates, and required fluid bottles. Note that capillary arrays are consumables with a lifespan of 1 year or 1,000 injections; replacement arrays must be purchased separately from Agilent.

This instrument is widely adopted in biotechnology sectors for applications such as oligonucleotide purity control, DNA/RNA fragment sizing and quantification, mRNA and antisense oligo analysis, and quality control in CRISPR and gene editing workflows. It is an essential tool supporting molecular diagnostics, biomanufacturing, and nucleic acid integrity assessment in clinical diagnostics and biomedical engineering research.

The instrument undergoes comprehensive functionality testing, including power, software communication, fluid handling, plate manipulation, and high-voltage operations, ensuring full operational reliability upon delivery.

Ideal for research professionals and laboratory buyers in molecular biology, biotechnology, and clinical diagnostics seeking a robust, automated solution for nucleic acid analysis with emphasis on high-throughput performance and precise UV absorbance detection.