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Nikon Ti2-E PFS N-SIM Super-Resolution Inverted Motorized Microscope with Dual Fluorescence Illumination
Product Description
The Nikon Ti2-E PFS N-SIM is an advanced super-resolution inverted motorized microscope designed for high-precision biomedical imaging and biotechnology research. It integrates dual fluorescence illumination combining a laser-based structured illumination (SIM) system and a widefield LED fluorescence source, ideal for quantitative multi-channel fluorescence and live-cell imaging workflows.
Key technical features include:
- Motorized microscope base and components: 6-position motorized objective turret with Plan Apo and Apo oil immersion objectives; motorized dual 6-position filter cube turrets; motorized emission filter wheel.
- Dual fluorescence illumination paths integrating the Nikon LU-N3-SIM laser illuminator and Lumencor Sola LED light source for flexible excitation sources suitable for a broad range of fluorescent dyes and biotech applications including molecular diagnostics and gene editing studies.
- High-sensitivity Hamamatsu ORCA-Flash4.0 sCMOS camera supports fast and low-noise acquisition critical in bioprocessing and synthetic biology research.
- Perfect Focus System (PFS) enables stable long-term time-lapse imaging by actively maintaining focus, essential for live-cell imaging experiments.
- Motorized XY stage with piezo nanopositioning allows automated tile scanning, multi-position sample acquisition, and fast Z-stack collection for 3D reconstruction and large-area mapping, widely used in neuroimaging and cellular analysis.
- NIS-Elements AR software, providing multi-dimensional acquisition (XY, Z, time, multiple channels), automated stage mapping, tile scan stitching, and hardware synchronization to optimize fluorescence imaging workflows.
Additional configurable options allow customization to fit specific research needs: addition of phase contrast, DIC or polarization modules; high-NA Nikon apochromat objectives; expanded filter sets compatible with diverse fluorophores such as DAPI, FITC, Texas Red, and Cy5; upgraded high-end CCD, EMCCD cameras; and enhanced illumination sources (Xenon, Metal Halide, or LED).
This system suits a broad range of laboratory applications, including:
- High-resolution fluorescence imaging and super-resolution structured illumination microscopy
- Quantitative fluorescence analysis for molecular biology and synthetic biology
- Live-cell imaging with environmental stability for biomanufacturing process monitoring
- Automated plate imaging and high-content screening in clinical diagnostics
- Materials science and thin-film inspection using transmitted and fluorescence light
The N-SIM module, while included, requires professional setup by Nikon technicians for full super-resolution capability. The microscope is fully serviced, field-tested for distortion and fluorescence intensity uniformity, and shipped with a warranty and optional training. It is widely adopted in advanced biotechnological imaging workflows where precision and automation are critical.
This Nikon Ti2-E system enables researchers, biotechnologists, and clinical professionals to conduct complex multi-channel fluorescence experiments with automated controls and high fidelity, supporting rigorous molecular diagnostics, gene editing analyses, and bioprocessing imaging pipelines.
Item Stats
Product details
| Stock | In Stock |
| Brand | Nikon |
| Product Code | 61818-V2 |
| Condition | Pre-Owned |
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