Revvity PerkinElmer Operetta CLS Automated High Content Cellular Imaging System

The Revvity PerkinElmer Operetta CLS High Content Analysis System is a benchtop automated microscopy platform designed for advanced cellular imaging and phenotypic profiling. It integrates multiplex fluorescence excitation with high-power LEDs (365 nm UV, 475 nm, 550 nm, and 630 nm) and brightfield imaging via a 740 nm LED transmission source, supporting versatile assay modalities essential in drug discovery screening and live-cell time-lapse studies.

Key technical specifications include:

This instrument is widely adopted in biotechnology and molecular diagnostics laboratories, where consistent, automated high-resolution imaging supports molecular cloning workflows, synthetic biology research, and biopharmaceutical production pipelines. The combination of fluorescence and transmitted light imaging modes enables comprehensive cellular assays, including phenotypic profiling and quantitative live-cell imaging critical for bioprocessing applications.

Designed for ease of integration in research and clinical labs, the Operetta CLS features a compact benchtop design, allowing deployment in space-conscious environments. This system is currently offered as pre-owned, sold as-is, and untested due to the absence of a software dongle; however, it is supported by a dedicated technical service team and compatible with standard Operetta CLS software configurations.

This high content analysis system is an essential tool for researchers focusing on cellular imaging with fluorescence and brightfield modalities, particularly those engaged in biomedical engineering, cell biology, and clinical diagnostics requiring robust, automated imaging solutions.