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Solentim Cell Metric VIPS Single Cell Seeder with Cell Metric CLD High Contrast Imager Monoclonality System
Product Description
The Solentim Cell Metric VIPS Single Cell Seeder combined with the Cell Metric CLD High Contrast Imager offers an integrated platform for precision single-cell cloning and clonal growth monitoring, essential in biotechnology, molecular diagnostics, and biopharmaceutical development. This system supports workflows from gentle nanoliter droplet seeding of fragile cells (e.g., iPSCs, CHO, HEK293) to automated high-resolution imaging for clonality proof and colony growth assessment.
Key technical features include:
- Low-pressure nanoliter droplet dispensing (<1 psi) for verified gentle single-cell seeding minimizing cell stress.
- In-well Z-stack imaging at 20 focal planes per well ensures robust depth resolution with laser autofocus compensating for plate contour variations.
- Two-step clonality verification: immediate cell presence confirmation post-seeding followed by daily monitoring of clonal proliferation.
- Automated inline media dispensing integrated with seeding and imaging processes to enhance culture consistency.
- Cell Metric CLD High Contrast Imager features a temperature-controlled 10-plate heated stacker allowing unattended batch scanning to boost throughput.
- Compatible with multiple 96-well plate types (BD Falcon, Corning CellBIND, Eppendorf, Greiner, Nunc, TPP).
- Imaging parameters: 10x objective magnification, 650 nm laser wavelength, ~850 µW max average laser power, with a typical clonality verification time of 4–5 minutes per plate.
- Advanced Cell Metrics software suite supporting GPU-accelerated image processing, clonality reports, fluorescence verification, and detailed growth monitoring essential for molecular cloning workflows and synthetic biology research.
This system is widely adopted in bioprocessing and biomanufacturing pipelines to generate clonal cell lines with documented monoclonality, a critical requirement for regulatory compliance in gene editing, cell line development, and biopharmaceutical production. It significantly improves efficiency over limiting dilution cloning by reducing manual interventions and ensuring high accuracy in single-cell origin validation.
The included computer and software licenses enable automated instrument control, barcode reading, and integrative results management, facilitating seamless operation within cell line development and live-cell imaging applications.
Overall, the Solentim Cell Metric VIPS + CLD system is an essential tool for researchers aiming to enhance cell cloning fidelity and optimize cell line stability, supporting advanced biotechnology and clinical diagnostic workflows.
Keywords: single cell seeder, clonality verification, high contrast imager, cell line development system, biotechnology cell cloning, molecular diagnostics equipment, biopharmaceutical production, synthetic biology research, live-cell imaging system, automated cell seeding, cell growth monitoring, monoclonality proof, nanoliter droplet dispensing, 96-well plate imaging.
Item Stats
Product details
| Stock | In Stock |
| Brand | Advanced Instruments |
| Product Code | 66842 |
| Condition | Pre-Owned |
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