Covaris ML230 Focused Ultrasonicator with Adaptive Focused Acoustics Technology

The Covaris ML230 Focused Ultrasonicator is a benchtop instrument utilizing Adaptive Focused Acoustics (AFA) technology, delivering controlled and reproducible ultrasonic energy to biological samples. Engineered for molecular biology and biotechnology applications, it supports simultaneous processing of 1 to 8 samples with sample volumes ranging from 5 to 50 µL, optimal for next-generation sequencing (NGS) workflows.

Key technical specifications include:

The instrument features an automated water management system maintaining consistent acoustic conditions and a built-in touchscreen interface for streamlined workflow setup, method import/export via USB, and real-time process monitoring. This reduces operator variability and cross-contamination risks, making it essential for protocols including DNA shearing for NGS, chromatin shearing for ChIP assays, RNA extraction, protein extraction from tissues, cell lysis, homogenization, and formalin-fixed paraffin-embedded (FFPE) sample processing.

Notably, the ML230 operates with non-contact acoustics, enhancing sample integrity and reliability for sensitive molecular diagnostics workflows and bioprocessing tasks. The system's compact footprint suits constrained lab spaces, making it widely adopted in synthetic biology, molecular cloning workflows, and biopharmaceutical production pipelines.

Accessories and consumables, including various AFA microTUBEs and tube racks, are application-specific and available separately to customize for research needs. The instrument comes fully tested, serviced, and warranted, with technical support and training options to ensure optimal integration into clinical diagnostics and biotechnology research environments.

This focused ultrasonicator is a critical tool for laboratories engaged in gene editing, molecular diagnostics, biomanufacturing, and live-cell imaging sample preparation, providing reproducible ultrasonic processing that enhances the quality and throughput of advanced biotechnological applications.