Molecular Devices ImageXpress Micro 4 High Content Imaging System with sCMOS Camera and Environmental Control

The Molecular Devices ImageXpress Micro 4 is a high-content imaging system engineered for advanced cell-based assays, drug discovery, and diverse biomedical research applications. This automated widefield fluorescence microscope integrates a high-resolution >4 megapixel sCMOS camera, five-channel illumination via a 5-position filter changer, and a 4-position objective turret supporting air objectives from 1× to 100× and oil objectives at 40×, 60×, and 100× magnifications. The system achieves rapid data acquisition speeds exceeding 200,000 wells per day and supports imaging plates up to 1536 wells.

Key imaging modalities include brightfield, phase contrast, and transmitted light, complemented by laser and image autofocus for enhanced precision. Environmental control is supported by accessories such as the Live Cell Instrument FC-9 Gas Mixer enabling CO2 and temperature regulation, essential for live-cell imaging and longitudinal phenotypic profiling in synthetic biology and molecular diagnostics workflows. This configuration is compatible with robotic automation to facilitate integration into bioprocessing pipelines and high-throughput screening environments.

Primary applications span 3D cell models, cardiomyocyte analysis, neurite outgrowth/tracing, oncology, toxicology, stem cell research, and infectious disease studies including COVID-19. Widely used in molecular biology, biopharmaceutical production, and biomedical engineering, the ImageXpress Micro 4 supports customizable imaging protocols through open module editors.

Please note: This pre-owned unit is sold as-is, untested by the seller, without included MetaXpress software which must be purchased separately from Molecular Devices. Shipping is offered with fully insured freight, with safe packaging in ISPM15-certified wooden crates for international and domestic deliveries, ensuring protection of sensitive optical and mechanical components.

Overall, the ImageXpress Micro 4 is a versatile, high-throughput, and automated imaging platform critical for gene editing validation, phenotypic screening, and biomanufacturing research requiring precise quantitative microscopy in a controlled cellular environment.