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The Genexus Integrated Sequencer automates all steps of the targeted NGS workflow starting from purified and quantified nucleic acid. With a single touchpoint and five minutes of hands-on time, the Genexus sequencer automates NGS library preparation (including cDNA synthesis), template preparation, sequencing, primary data analysis, and variant reporting for DNA, RNA, and cfTNA applications. Sequencing on the Genexus sequencer is done on a four-lane semiconductor chip: the Ion Torrent GX5 Chip. Each of the four lanes of the GX5 Chip supports the output of 12–15 million reads, and they can be used individually or all at once depending on throughput needs. Ion Torrent Genexus Software streamlines the NGS workflow by integrating the setup-to-report workflow within a single software ecosystem.
• Rapidly go from nucleic acid to report in a single day
• Simplify the NGS workflow with a single instrument that can automate library prep, sequencing, and analysis, including variant calling
• Modulate run setup as samples come in with the flexibility of multiplexing up to 32 library reactions per run in increments of four
• Simultaneously create libraries and sequence up to four different assays using the four-lane GX5 Chip
• Reduce NGS operating costs with simplified setup using pre-filled reagents, a single touchpoint, and five minutes of total hands-on time
• Prevent user error by allowing the Genexus sequencer’s onboard vision system to verify reagent placement and detect errors in real time
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