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Axon Axopatch 200B Patch Clamp Amplifier System with CV 203BU Headstage, Digidata 1440A Digitizer, and pCLAMP 11 Software
Product Description
The Axon Axopatch 200B Patch Clamp Amplifier System includes the Axopatch 200B low-noise microelectrode amplifier with the CV 203BU headstage, the Axon Digidata 1440A digitizer, and the pCLAMP 11 software suite for advanced electrophysiology research.
Key amplifier specifications:
- Model: Axopatch 200B by Axon Instruments
- Design: High-precision, low-noise patch clamp amplifier ideal for whole-cell, cell-attached, inside-out, and outside-out patch configurations
- Headstage: CV 203BU single-channel with high input impedance and low capacitance, compatible with standard micropipette holders
- Features: Integrated capacitive and resistive compensation, switchable voltage clamp and current clamp modes
- Filters: Built-in low-pass Bessel filter with selectable cutoff frequencies
- Outputs: Scaled analog outputs (I_Mon, V_Mon, Command) for real-time signal monitoring
Digitizer details:
- Model: Axon Digidata 1440A A/D and D/A digitizer
- Connectivity: USB 2.0 interface to PC
- Sampling rate: Up to 250 kHz per channel
- Resolution: 16-bit A/D conversion
- Channels: 8 analog inputs, 4 analog outputs, 8 digital inputs, 8 digital outputs
- Ensures precise data acquisition with minimal latency
Software and system integration:
- Data acquisition PC equipped with pCLAMP 11 software (includes Clampex and Clampfit modules) licensed and USB dongle included
- Real-time control and automated experimental protocols with customizable stimulation templates, automated pulse generation, seal test, and leakage subtraction
- Advanced event detection and signal filtering for post-recording data analysis
Applications and relevance:
- Essential for electrophysiology studies including ion channel characterization, synaptic physiology, pharmacology assays, membrane biophysics, and cell excitability research
- Widely used in neuroscience, molecular diagnostics, and biotechnology research, especially critical for bioprocessing and gene editing studies necessitating precise membrane voltage control
- Supports biomanufacturing and synthetic biology workflows requiring high-fidelity electrophysiological recordings
Package inclusions:
- Axopatch 200B amplifier main unit
- CV 203BU headstage
- Axon Digidata 1440A digitizer with USB cable
- Headstage connection cable, power cables, signal connectors
- Data acquisition PC with pCLAMP 11 license and USB dongle
Additional options available:
- Pipette holders, additional headstages, vibration isolation tables, Faraday cages, patch clamp micromanipulators, perfusion systems, and stimulus isolators
This system delivers a comprehensive electrophysiology solution optimized for high-resolution voltage-clamp and current-clamp experiments, suitable for advanced research in neuroscience and biotechnology involving live-cell imaging and molecular diagnostics. The Axopatch 200B with Digidata 1440A and pCLAMP 11 software provides a robust platform for precise ion channel recordings and is widely adopted in synthetic biology research and biopharmaceutical production pipelines.
Keywords included: patch clamp amplifier, electrophysiology data acquisition, voltage clamp, current clamp, ion channel characterization, neuroscience research, molecular diagnostics, biotechnology research, bioprocessing, synthetic biology, biomanufacturing, live-cell imaging, membrane potential recording.
Item Stats
Product details
| Stock | In Stock |
| Brand | Axon |
| Product Code | SM100021-1440A |
| Condition | Pre-Owned |
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